Dasacent 5050mg
Tablet
Incepta Pharmaceuticals Ltd.
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| Alcohol | CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Dasacent 50. Please consult your doctor. |
| Pregnancy | CONSULT YOUR DOCTOR Dasacent 50 is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it ... View More |
| Breastfeeding | UNSAFE Dasacent 50 is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby. |
| Driving | UNSAFE Dasacent 50 may cause side effects which could affect your ability to drive.
Take special care when driving in case you experience side effects such as ... View More |
| Kidney | SAFE IF PRESCRIBED Dasacent 50 is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Dasacent 50 may not be need... View More |
| Liver | SAFE IF PRESCRIBED Dasacent 50 is safe to use in patients with liver disease. No dose adjustment of Dasacent 50 is recommended. |
Introduction
Dasacent 50 is used in the treatment of blood cancer (chronic myeloid leukaemia). It is used in patients whose disease could not be treated with other m... View More
Uses of Dasacent 50
- Blood cancer (Chronic myeloid leukaemia)
Side effects of Dasacent 50
- Abdominal pain
- Anemia (low number of red blood cells)
- Breathing problems
- Fatigue
- Fever
- Headache
- Infection
- Low blood platelets
- Musculoskeletal (bone, muscle or joint) pain
- Nausea
- Rash
- Vomiting
How to use Dasacent 50
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Dasacent 50 may be taken w... View More
How Dasacent 50 works
Dasacent 50 is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to s... View More
What if you forget to take Dasacent 50?
If you miss a dose of Dasacent 50, skip it and continue with your normal schedule. Do not double the dose.
- Take it with or without food, preferably at the same time each day.
- Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn't stop or if you find blood in your stools.
- Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
- Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe... View More
- It may cause serious bleeding problem. Inform your doctor if you get headaches, stomach pain or if you notice blood in your urine or stools.
- Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.
Indication
Chronic myeloid leukaemia
Administration
May be taken with or without food. Swallow whole, do not break/crush/cut.
Adult Dose
Oral Chronic myeloid leukaemia Adult: Chronic phase CML: Initially, 100 mg once daily, may increase up to 140 mg once daily. Accelerated, myeloid or l... View More
Contraindication
Concomitant use w/ CYP3A4 inhibitors (e.g. atazanavir, clarithromycin, erythromycin, indinavir, itraconazole, ketoconazole, nefazodone, nelfinavir, rito... View More
Mode of Action
Dasatinib is an inhibitor of multiple tyrosine kinases. It is used for the treatment of all phases of chronic myeloid leukaemia (CML) and Philadelphia c... View More
Precaution
Patients w/ predisposing factors for QT prolongation (e.g. congenital long QT syndrome, hypokalaemia, hypomagnesaemia, on antiarrhythmic therapy, or rec... View More
Side Effect
>10% Fluid retention, incl CHF, pulm edema, pleural effusion (50%),Diarrhea (49%),Headache (40%),Hemorrhage (40%),Fatigue (39%),Pyrexia (39%),Skin rash... View More
Pregnancy Category Note
Pregnancy Based on limited human data, dasatinib can cause fetal harm when administered to a pregnant woman; adverse pharmacologic effects (eg, hydrops... View More
Interaction
Concomitant use w/ drugs that have narrow therapeutic index (e.g. alfentanil, cisapride, ciclosporin, fentanyl, pimozide, quinidine, simvastatin, siroli... View More
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More