Embelin 55mg
Tablet
Incepta Pharmaceuticals Ltd.
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| Alcohol | CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Embelin 5. Please consult your doctor. |
| Pregnancy | UNSAFE Embelin 5 is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful ef... View More |
| Breastfeeding | CONSULT YOUR DOCTOR Information regarding the use of Embelin 5 during breastfeeding is not available. Please consult your doctor. |
| Driving | CAUTION Embelin 5 may cause dizziness or weakness due to low blood pressure. Do not drive if these symptoms occur. |
| Kidney | CAUTION Embelin 5 should be used with caution in patients with severe kidney disease. Dose adjustment of Embelin 5 may be needed. Please consult your doctor.
Li... View More |
| Liver | CAUTION Embelin 5 should be used with caution in patients with liver disease. Dose adjustment of Embelin 5 may be needed. Please consult your doctor. |
Introduction
Embelin 5 is a prescription medicine used to treat pulmonary arterial hypertension (high pressure in the blood vessels that carry blood from the heart t... View More
Uses of Embelin 5
- Pulmonary arterial hypertension (PAH)
Side effects of Embelin 5
- Headache
- Dizziness
- Palpitations
- Breathlessness
- Runny nose
- Feeling sick
- Diarrhea
- Fatigue
How to use Embelin 5
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Embelin 5 may be taken wit... View More
How Embelin 5 works
Embelin 5 is an endothelin receptor blocker. It blocks the action of endothelin (a natural substance) that causes blood vessels to narrow (constrict). T... View More
What if you forget to take Embelin 5?
If you miss a dose of Embelin 5, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your... View More
- Your doctor has prescribed Embelin 5 to treat high pressure in the blood vessels that carry blood from the heart to the lungs (the pulmonary arteries).
- It helps improve your quality of life, exercising ability, and delay disease progression.
- Your doctor may ask you to get routine blood tests done to check for anemia and to assess the functioning of your liver.
- Do not drive or do anything requiring concentration until you know how Embelin 5 affects you.
- Notify your doctor if you are pregnant or planning to conceive or breastfeeding.
- Females with reproductive potential should use a reliable form of birth control while using and 1 month after stopping Embelin 5 as it is toxic to an un... View More
- Inform your doctor if you notice weight gain, swelling of your arms and legs, or difficulty breathing.
Indication
Pulmonary Arterial Hypertension
Administration
May be taken with or without food: Swallow whole.
Adult Dose
Indicated for WHO group 1 PAH to 1) improve exercise ability and delay clinical worsening; and 2) in combination with tadalafil to reduce the risks of d... View More
Child Dose
Safety and efficacy not established
Renal Dose
Dose adjustment in patients with mild or moderate renal impairment is therefore not required. There is no information on the exposure to ambrisentan in ... View More
Contraindication
Ambrisentan may cause fetal harm when administered to a pregnant woman. Ambrisentan is contraindicated in women who are or may becom... View More
Mode of Action
High affinity endothelin (ETa) receptor subtype antagonist, resulting in inhibition of vasoconstriction.
Precaution
Fluid Retention: Peripheral oedema has been observed with ERAs including ambrisentan. It is also a clinical consequence of PAH and worsening PAH. Pulm... View More
Side Effect
>10% Peripheral edema (17%),Headache (15%) 1-10% Nasal congestion (6%),Palpitations (5%),Constipation (4%),Dyspnea (4%),Flushing (4%),Abdominal pai... View More
Pregnancy Category Note
Pregnancy Based on data from animal reproduction studies, fetal harm may occur when administered to a pregnant woman and is contraindicated during preg... View More
Interaction
Cyclosporine Exposure to ambrisentan may be increased (approximately 2-fold). Limit the dosage of ambrisentan to 5 mg daily with coadministration. R... View More
Alternative brand for Embelin 5
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More