Imruza 5050mg
Tablet
Beacon Pharmaceuticals Ltd.
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| Alcohol | CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Imruza 50. Please consult your doctor. |
| Pregnancy | CONSULT YOUR DOCTOR Imruza 50 is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in... View More |
| Breastfeeding | CONSULT YOUR DOCTOR Imruza 50 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. |
| Driving | CONSULT YOUR DOCTOR It is not known whether Imruza 50 alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and r... View More |
| Kidney | CAUTION Imruza 50 should be used with caution in patients with kidney disease. Dose adjustment of Imruza 50 may be needed. Please consult your doctor.
Use of Im... View More |
| Liver | CAUTION Imruza 50 should be used with caution in patients with liver disease. Dose adjustment of Imruza 50 may be needed. Please consult your doctor.
Use of Imr... View More |
Introduction
Imruza 50 belongs to a group of medicines called immunosuppressants. It is used with other medicines to prevent your body rejecting an organ (such as a ... View More
Uses of Imruza 50
- Prevention of organ rejection in transplant patients
- Rheumatoid arthritis
Side effects of Imruza 50
- Decreased white blood cell count
- Increased bleeding tendency
- Nausea
- Infection
- Loss of appetite
How to use Imruza 50
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Imruza 50 is to be taken w... View More
How Imruza 50 works
Imruza 50 is an immunosuppressant. It reduces the action of body's own defense system (the immune system) and prevents rejection of the transplanted org... View More
- Your doctor has prescribed Imruza 50 to stop the body from rejecting a transplanted organ (e.g. kidney, heart or liver).
- Imruza 50 also relieves joint pain and inflammation in rheumatoid arthritis.
- You may have to take additional medications along with Imruza 50 for better relief of symptoms.
- Avoid contact with people who have cold, flu or other contagious illness. Notify your doctor if you have any signs of infection such as a fever or sore ... View More
- Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
Indication
Rheumatoid arthritis, Prevention of rejection in organ and tissue transplantation, Auto-immune diseases, Renal homotransplantation
Administration
May be taken with or without food. Preferably taken w/ or after meals to reduce GI discomfort.
Adult Dose
Rheumatoid Arthritis 1 mg/kg/day PO initially in single daily dose or divided q12hr; may be increased by 0.5 mg/kg/day after 6-8 weeks, then by 0.5 mg/... View More
Child Dose
Juvenile Idiopathic Arthritis 1 mg/kg/day PO initially in single daily dose or divided q12hr; may be increased by 0.5 mg/kg/day after 6-8 weeks, then b... View More
Renal Dose
Reduce dose.
Contraindication
Hypersensitivity; previous treatment with alkylating agents; pregnancy, lactation.
Mode of Action
Azathioprine is an imidazolyl derivative of mercaptopurine, which inhibits DNA, RNA and protein synthesis and antagonises purine synthesis. It also inhi... View More
Precaution
Increased risk of serious infections and neoplasia in chronic immunosuppression; leucopenia, thrombocytopenia, renal or hepatic impairment. Increased ri... View More
Side Effect
>10% Leukopenia (28-50%),Infection (20%) <1% Lymphoma Frequency Not Defined Fever, chills; bone marrow depression, thrombocytopenia or anaemi... View More
Pregnancy Category Note
Pregnancy category: D Lactation: Drug excreted at low levels in breast milk; use not recommended
Interaction
Increased risk of haematotoxicity with aminosalicylates, drugs that affect myelopoesis e.g. co-trimoxazole or trimethoprim. Increased risk of infections... View More
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More