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Corestin 55mg

Tablet
rx_reqRequire Prescription
Unimed Unihealth Pharmaceuticals Ltd.
Generic: Rosuvastatin
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descriptionSafety Advices
AlcoholAlcohol
CAUTION
Caution is advised when consuming alcohol with Corestin 5. Please consult your doctor.
PregnancyPregnancy
UNSAFE
Corestin 5 is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful e... View More
BreastfeedingBreastfeeding
UNSAFE
Corestin 5 is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
DrivingDriving
SAFE
Corestin 5 does not usually affect your ability to drive.
KidneyKidney
CAUTION
Corestin 5 should be used with caution in patients with kidney disease. Dose adjustment of Corestin 5 may be needed. Please consult your doctor. Use of ... View More
LiverLiver
CAUTION
Corestin 5 should be used with caution in patients with liver disease. Dose adjustment of Corestin 5 may be needed. Please consult your doctor. Use of C... View More
descriptionMedical Overview

Introduction

Corestin 5 belongs to a group of medicines called statins. It is used to lower cholesterol and to reduce the risk of heart disease. Cholesterol is a fat... View More

Uses of Corestin 5

  • High cholesterol
  • Prevention of heart attack and stroke

Side effects of Corestin 5

Common
  • Muscle pain
  • Weakness
  • Headache
  • Abdominal pain

How to use Corestin 5

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Corestin 5 may be taken wi... View More

How Corestin 5 works

Corestin 5 is a lipid-lowering medication (statin). It works by blocking an enzyme (HMG-CoA-reductase) that is required by the body to make cholesterol,... View More

What if you forget to take Corestin 5?

If you miss a dose of Corestin 5, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to you... View More

quick tipsQuick Tips
  • Corestin 5 treats high cholesterol by lowering "bad" cholesterol (LDL) and triglycerides (fats). It should be taken in addition to regular exercise and ... View More
  • In general, Corestin 5 is safe. It may cause diarrhea, gas or an upset stomach. If any of these happen to you, take it with food.
  • Inform your doctor if you experience fatigue, muscle weakness or muscle pain.
  • Your doctor may check your liver function before starting the treatment and regularly thereafter. Inform your doctor if you notice signs of liver proble... View More
  • Inform your doctor if you have kidney disease, liver disease or diabetes before starting treatment with this medicine. If you are diabetic, monitor your... View More
  • Do not take Corestin 5 if you are pregnant, planning a pregnancy or breastfeeding.
descriptionBrief Description

Indication

Hyperlipidaemias, Primary hypercholesterolaemia (heterozygous familial hypercholesterolaemia), mixed dyslipidaemia, homozygous familial hypercholesterol... View More

Administration

May be taken with or without food.

Adult Dose

Oral Hypercholesterolemia, Hypertriglyceridemia, hyperlipidemia, mixed dyslipidemiaProphylaxis of cardiovascular events in high-risk patients Adult: I... View More

Child Dose

Oral Child Heterozygous familial hypercholesterolaemia: >10 yr Initially, 5 mg once daily, may be adjusted at intervals of at least 4 wk. Max: 20 mg... View More

Renal Dose

Renal impairment Severe (CrCl <30 mL/min/1.73m²) and not on hemodialysis: Decrease starting dose to 5 mg PO qDay; not to exceed 10 mg PO qDay CrCl>30m... View More

Contraindication

Severe renal impairment, active liver disease, unexplained persistent elevations of serum transaminases; hypersensitivity. Pregnancy, lactation.

Mode of Action

Rosuvastatin is a selective and competitive inhibitor of HMG-CoA reductase, the rate-limiting enzyme in cholesterol synthesis. It increases the number o... View More

Precaution

Patients w/ predisposing factors for myopathy (e.g. untreated hypothyroidism, renal impairment), history of chronic liver disease and alcoholism. Monito... View More

Side Effect

>10% Myalgia (3-13%) 1-10% Arthralgia (10%),Diabetes mellitus, new onset (3%),Pharyngitis (9%),Headache (6%),Asthenia (up to 5%),Dizziness (4%),CPK... View More

Interaction

May increase serum levels of warfarin and oral contraceptives. May increase serum levels w/ itraconazole, HIV protease inhibitors. May decrease serum le... View More

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descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More