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Hallmark Pharmaceuticals Ltd.
Generic: Cyclobenzaprine Hydrochloride
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descriptionSafety Advices
Cyrin may cause excessive drowsiness with alcohol.
Cyrin is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there a... View More
Cyrin is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Cyrin may cause side effects which could affect your ability to drive.
There is limited information available on the use of Cyrin in patients with kidney disease. Please consult your doctor.
Cyrin should be used with caution in patients with liver disease. Dose adjustment of Cyrin may be needed. Please consult your doctor. Use of Cyrin is no... View More
descriptionMedical Overview


Cyrin is a muscle relaxer. It provides relief from the discomfort associated with acute, painful musculoskeletal conditions such as rigidity, tension, s... View More

Uses of Cyrin

  • Muscle relaxation

Side effects of Cyrin

  • Sleepiness
  • Dryness in mouth

How to use Cyrin

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Cyrin is to be taken with ... View More

How Cyrin works

Cyrin is a muscle relaxant. It works on the centres in the brain and spinal cord to relieve muscle stiffness or spasm without reduction in strength. Thi... View More

What if you forget to take Cyrin?

If you miss a dose of Cyrin, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your reg... View More

quick tipsQuick Tips
  • Skelebenz 15 Capsule ER provides relief from rigidity, tension and stiffness in muscles (spasticity) that may occur due to various conditions affecting ... View More
  • Take it with or after food or a glass of milk.
  • Skelebenz 15 Capsule ER may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
  • Avoid consuming alcohol when taking Skelebenz 15 Capsule ER as it may cause excessive drowsiness.
  • Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
  • Do not stop taking it suddenly without talking to your doctor if you've been on it for a long time.
descriptionBrief Description


Fibromyalgia, Muscle spasm

Adult Dose

Oral Painful muscle spasm associated with musculoskeletal conditions Adult: 5 mg tid, may increase to 10 mg tid if needed. Treatment should not last m... View More

Child Dose

Muscle Spasm Oral <15 years: Safety and efficacy not established >15 years: 5 mg PO q8hr; may increase dose to 10 mg PO q8hr PRN


Recent MI, arrhythmias, severe liver disease.

Mode of Action

Cyclobenzaprine, a centrally-acting skeletal muscle relaxant, is structurally related to tricyclic antidepressants, thus they share similar properties. ... View More


Cardiac disease, history of epilepsy, hepatic impairment, hyperthyroidism, pheochromocytoma, history of mania, psychoses, close-angle glaucoma, history ... View More

Side Effect

>10% Drowsiness (up to 39% immediate-release),Dry mouth (21-32%),Dizziness (3-11%) 1-10% Pharyngitis (1-3%),Headache (1-5%),Fatigue (6%),Palpitatio... View More

Pregnancy Category Note

Pregnancy Available data from case reports with use in pregnancy have not identified a drug-associated risk of major birth defects, miscarriage, or adv... View More


Plasma concentration may be increased with the use of cimetidine, diltiazem, disulfiram, methylphenidate, ritonavir, and verapamil. Side-effects are inc... View More

Alternative brand for Cyrin
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More

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