Simpli-3500mg
Tablet
Beacon Pharmaceuticals Ltd.
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| Alcohol | UNSAFE It is unsafe to consume alcohol with Simpli-3. |
| Pregnancy | SAFE IF PRESCRIBED Simpli-3 is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, ther... View More |
| Breastfeeding | SAFE IF PRESCRIBED Simpli-3 is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not h... View More |
| Driving | SAFE Simpli-3 does not usually affect your ability to drive. |
| Kidney | CAUTION Simpli-3 should be used with caution in patients with severe kidney disease. Dose adjustment of Simpli-3 may be needed. Please consult your doctor. |
| Liver | CAUTION Simpli-3 should be used with caution in patients with liver disease. Dose adjustment of Simpli-3 may be needed. Please consult your doctor. |
Introduction
Simpli-3 is an antibiotic used to treat various types of bacterial infections of the respiratory tract, ear, nose, throat, lungs, skin, and eye in adult... View More
Uses of Simpli-3
- Bacterial infections
Side effects of Simpli-3
- Vomiting
- Nausea
- Abdominal pain
- Diarrhea
How to use Simpli-3
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Simpli-3 may be taken with... View More
How Simpli-3 works
Simpli-3 is an antibiotic. It works by preventing synthesis of essential proteins required by bacteria to carry out vital functions. Thus, it stops the ... View More
What if you forget to take Simpli-3?
If you miss a dose of Simpli-3, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your ... View More
- Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection to come back and harder ... View More
- Take it 1 hour before or two hours after food.
- Do not take antacids 2 hours before or after taking Simpli-3.
- Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your sto... View More
- Stop taking Simpli-3 and inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties w... View More
Indication
Bacterial infections, bacterial endocarditis, typhoid fever, community-acquired pneumonia, uncomplicated gonorrhea, streptococcal pharyngitis/tonsilliti... View More
Administration
Oral Administration Tablet: Take tablets without regard to food; however, food may enhance tolerability Oral suspension Conventional oral suspensio... View More
Adult Dose
Adult: PO Resp tract infections; Skin and soft tissue infections 500 mg once daily for 3 days. Chancroid; Non-gonococcal cervicitis/urethritis due t... View More
Child Dose
Child: PO: q24h Otitis: 10 mg/kg/day for 1 day, then 5 mg/kg for 4 days; or 10 mg/kg/day for 3 days; or 30 mg/kg once. Pharyngitis: 12 mg/kg/day for ... View More
Renal Dose
Renal impairment: No dosage adjustment needed.
Contraindication
Known hypersensitivity to azithromycin, erythromycin, any macrolide or ketolide antibiotic. Coadministration w/ pimozide. History of cholestatic jaundic... View More
Mode of Action
Azithromycin is a semisynthetic azalide antibiotic. It blocks transpeptidation by binding to 50s ribosomal subunit of susceptible organisms and disrupti... View More
Precaution
May increase the risk of Torsades de pointes and fatal heart arrhythmias in patients w/ prolonged QT interval, low K or Mg blood levels, slow heart rate... View More
Side Effect
>10% High single dose therapy Diarrhea (52.8%),Nausea (32.6%),Abdominal pain (27%),Loose stool (19.1%) 1-10% Cramping (2-10%),Vaginitis (2-10%),Dy... View More
Pregnancy Category Note
Pregnancy Available data from published literature and postmarketing experience over several decades with azithromycin use in pregnant women have not i... View More
Interaction
Increases serum concentrations of digoxin, ciclosporin, terfenadine, hexobarbital and phenytoin. Decreased rate of absorption w/ antacids containing alu... View More
Alternative brand for Simpli-3
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More