Desirox Dis500mg
Tablet
Cipla Ltd.
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| Alcohol | CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Desirox Dis. Please consult your doctor. |
| Pregnancy | CONSULT YOUR DOCTOR Desirox Dis may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the develo... View More |
| Breastfeeding | SAFE IF PRESCRIBED Desirox Dis is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.... View More |
| Driving | UNSAFE Desirox Dis may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. |
| Kidney | UNSAFE Desirox Dis is probably unsafe to use in patients with kidney disease and should be avoided. Please consult your doctor. |
| Liver | CAUTION Desirox Dis should be used with caution in patients with liver disease. Dose adjustment of Desirox Dis may be needed. Please consult your doctor.
Limite... View More |
Introduction
Desirox Dis is a medicine used in the treatment of chronic iron overload caused by frequent blood transfusion. It helps remove the excess iron from the ... View More
Uses of Desirox Dis
- Iron overload
- Transfusion dependent thalassemia
Side effects of Desirox Dis
- Nausea
- Headache
- Vomiting
- Rash
- Abdominal pain
- Constipation
- Itching
- Increased liver enzymes
- Abdominal distension
- Diarrhea
How to use Desirox Dis
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Desirox Dis is to be taken... View More
How Desirox Dis works
Desirox Dis traps and removes excess iron which is then excreted mainly in the stools. This reduces the risk of organ damage.
What if you forget to take Desirox Dis?
If you miss a dose of Desirox Dis, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to yo... View More
- Always take deferasirox tablet on an empty stomach by dissolving into a glass of water.
- Do not chew, crush, break or swallow the tablets as a whole.
- Deferasirox may cause dizziness. It is advisable not to drive or operate any machinery until you feel normal again.
- Avoid taking deferasirox if you are pregnant, planning to become pregnant or are breast feeding.
Indication
Chronic iron overload.
Administration
Should be taken on an empty stomach. Take on an empty stomach at least 30 min before meals preferably at the same time daily. Disperse tab completely by... View More
Adult Dose
Transfusional Hemosiderosis Indicated for treatment of chronic iron overload caused by blood transfusion 20 mg/kg PO qDay; may increase by 5-10 mg inc... View More
Child Dose
Transfusional Hemosiderosis Indicated for treatment of chronic iron overload caused by blood transfusion <2 years: Safety and efficacy not established... View More
Renal Dose
Renal Impairment Baseline renal impairment CrCl 40-60 mL/min: Reduce starting dose by 50% Serum Cr >2 xULN or CrCl <40 mL/min: Do not use
Contraindication
Hypersensitivity.
Mode of Action
Deferasirox is an orally active chelator that is selective for iron (as Fe3+ ion). It is a tridentate ligand that binds iron with high affinity in a 2:1... View More
Precaution
Monitor renal function and CBC before starting treatment and regularly during treatment; may need to reduce dose or stop treatment if serum creatinine l... View More
Side Effect
>10% Serum creatinine increase (dose related; 7-38%),Abdominal pain (21-28%),Nausea (11-23%),Vomiting (10-21%),Diarrhea (12-20%),Proteinuria (19%),Pyre... View More
Pregnancy Category Note
Pregnancy There are no studies with use in pregnant women to inform drug-associated risks; administration of deferasirox to rats during pregnancy resul... View More
Interaction
Not to be used with aluminium-containing antacids as it may chelate aluminium.
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More