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Detrusin1mg

Tablet
rx_reqRequire Prescription
Unimed Unihealth Pharmaceuticals Ltd.
Generic: Tolterodine Tartrate
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2.50
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descriptionSafety Advices
AlcoholAlcohol
UNSAFE
Detrusin may cause excessive drowsiness with alcohol.
PregnancyPregnancy
CONSULT YOUR DOCTOR
Detrusin may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developin... View More
BreastfeedingBreastfeeding
SAFE IF PRESCRIBED
Detrusin is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. Lo... View More
DrivingDriving
UNSAFE
Detrusin may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
KidneyKidney
CAUTION
Detrusin should be used with caution in patients with kidney disease. Dose adjustment of Detrusin may be needed. Please consult your doctor.
LiverLiver
CAUTION
Detrusin should be used with caution in patients with liver disease. Dose adjustment of Detrusin may be needed. Please consult your doctor.
descriptionMedical Overview

Introduction

Detrusin is used in the treatment of overactive bladder. It relieves urinary symptoms like frequent urination, urgent need to urinate and inability to c... View More

Uses of Detrusin

  • Overactive bladder (OAB) symptoms

Side effects of Detrusin

Common
  • Dryness in mouth
  • Constipation
  • Headache
  • Dizziness
  • Sleepiness
  • Blurred vision
  • Dry skin

How to use Detrusin

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Detrusin may be taken with... View More

How Detrusin works

Detrusin is an antimuscarinic. It works by relaxing muscles of the urinary bladder and prevents frequent, urgent or uncontrolled urination.

What if you forget to take Detrusin?

If you miss a dose of Detrusin, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your ... View More

quick tipsQuick Tips
  • Detrusin treats symptoms of an overactive bladder by lowering the urge to urinate and controlling urination.
  • It can take up to 4 weeks before you see any improvement in your symptoms. Keep taking it as prescribed.
  • Avoid caffeine, alcohol, and carbonated drinks as they can worsen your symptoms.
  • It may cause dizziness and blurring of vision. Don't drive or do anything that requires mental focus until you know how it affects you.
  • Dry mouth, dry eyes, and constipation may occur as a side effect. Maintain good oral hygiene, drink water frequently, chew sugarless gum, and wear conta... View More
descriptionBrief Description

Indication

Overactive bladder

Adult Dose

Oral Overactive Bladder, Urge Incontinence Immediate release: 2 mg PO q12hr. Reduce to 1 mg bid if needed to reduce side effects. Extended release... View More

Child Dose

Child < 18 years: Not recommended

Renal Dose

Renal impairment CrCl 10-30 mL/min: Not to exceed 1 mg PO q12hr (immediate release) or 2 mg PO once daily (extended release) CrCl <10 mL/min: Not reco... View More

Contraindication

Severe ulcerative colitis, toxic megacolon, urinary retention, gastric retention, myasthenia gravis, uncontrolled narrow-angle glaucoma, pregnancy.

Mode of Action

Tolterodine is a competitive muscarinic receptor antagonist with actions similar to atropine. It is used in the management of urge urinary incontinence,... View More

Precaution

Bladder flow obstruction, GI obstructive disorders, renal or hepatic impairment, autonomic neuropathy, hiatus hernia, risk of decreased GI motility, pat... View More

Side Effect

>10% Dry mouth (40%) 1-10% Blurred vision,Constipation,Dizziness,Drowsiness,Dyspepsia,Headache,Xerophthalmia

Interaction

Increased risk of overdosage with potent CYP3A4 inhibitors e.g. macrolide antibiotics (erythromycin and clarithromycin), azole antifungals (e.g. ketocon... View More

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descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More

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