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Diafre850mg

Tablet
rx_reqRequire Prescription
Mystic Pharmaceuticals Ltd.
Generic: Metformin Hydrochloride
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descriptionSafety Advices
AlcoholAlcohol
UNSAFE
It is unsafe to consume alcohol with Diafre.
PregnancyPregnancy
SAFE IF PRESCRIBED
Diafre is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there ... View More
BreastfeedingBreastfeeding
SAFE IF PRESCRIBED
Diafre is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
DrivingDriving
CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
KidneyKidney
CAUTION
Diafre should be used with caution in patients with kidney disease. Dose adjustment of Diafre may be needed. Please consult your doctor. Use of Diafre i... View More
LiverLiver
CAUTION
Diafre should be used with caution in patients with liver disease. Dose adjustment of Diafre may be needed. Please consult your doctor. Diafre is genera... View More
descriptionMedical Overview

Introduction

Diafre is a medicine used to treat type 2 diabetes mellitus. It helps control blood sugar levels and thus prevent serious complications of diabetes. It ... View More

Uses of Diafre

  • Type 2 diabetes mellitus

Side effects of Diafre

Common
  • Nausea
  • Vomiting
  • Taste change
  • Diarrhea
  • Abdominal pain
  • Loss of appetite

How to use Diafre

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Diafre is to be taken with... View More

How Diafre works

Diafre is an anti-diabetic medication (biguanide). It works by lowering glucose production in the liver, delaying the absorption of sugar (glucose) from... View More

What if you forget to take Diafre?

If you miss a dose of Diafre, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your re... View More

quick tipsQuick Tips
  • You have been prescribed Diafre to control the blood sugar level and reduce the risk of diabetic complications such as heart attacks.
  • Chances of weight gain and low blood sugar are lesser with this medicine as compared to other diabetes medicines.
  • Hypoglycemia (low blood sugar level) may occur when taken along with other antidiabetic medicines, alcohol or on delaying/skipping a meal. Carry a sugar... View More
  • Tell your doctor immediately if you experience any deep or rapid breathing, persistent nausea, vomiting, and stomach pain as Diafre may cause a rare but... View More
  • Prolonged use of Diafre may lead to vitamin B12 deficiency which may lead to anemia, causing fatigue, pale skin, shortness of breath or headache. Notify... View More
  • Your doctor will monitor your blood sugar levels and kidney functions regularly while you are taking this medication.
descriptionBrief Description

Indication

Type 2 DM, Polycystic ovarian syndrome,

Administration

Should be taken with food.

Adult Dose

Oral Type 2 diabetes mellitus Adult: Conventional preparation: Initially, 500 mg bid or tid, or 850 mg 1-2 times daily, may increase gradually to 2000... View More

Child Dose

Oral Type 2 diabetes mellitus Child: >10 yr Initially, 500 mg 1-2 times daily or 850 mg once daily, may increase gradually to max 2000 mg daily in 2 o... View More

Renal Dose

Renal impairment Obtain eGFR before starting metformin eGFR <30 mL/min/1.73 m²: Contraindicated eGFR 30-45 mL/min/1.73 m²: Not recommended to initiat... View More

Contraindication

Acute or chronic metabolic acidosis with or without coma (including diabetic ketoacidosis). Renal failure, severe renal or hepatic impairment, acute con... View More

Mode of Action

Metformin is a biguanide w/ antihyperglycaemic effects, lowering both basal and postprandial plasma glucose. It decreases hepatic glucose production by ... View More

Precaution

Caution when used in patients with CHF especially in those with unstable or acute heart failure. Risk of lactic acid accumulation increases with the deg... View More

Side Effect

Anorexia, nausea, vomiting, diarrhoea, wt loss, flatulence, occasional metallic taste; weakness; hypoglycaemia; rash, malabsorption of vit B12. Chest di... View More

Interaction

Additive effect w/ sulfonylureas. Thiazide diuretics, corticosteroids, phenothiazines, OC, sympathomimetics, niacin, Ca channel blockers and isoniazid m... View More

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descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More

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