Domperidone is a prescription medicine used in the treatment of indigestion, nausea and vomiting. It blocks the substance on the brain that triggers nau... View More
Uses of Domperidone
Side effects of Domperidone
How to use Domperidone
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Domperidone is to be taken... View More
How Domperidone works
Domperidone is a prokinetic. It works on the region in the brain that controls vomiting. It also acts on the upper digestive tract to increase the movem... View More
What if you forget to take Domperidone?
If you miss a dose of Domperidone, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to yo... View More
Gastritis, Lactation, Migraine, Nausea and vomiting, Gastroparesis, Non ulcer dyspepsia
Should be taken on an empty stomach. Take 15-30 min before meals.
Oral Adults: Nausea and vomiting 10-20 mg 4-8 hrly. Max: 80 mg/day. Non ulcer dyspepsia 10 mg 3-4 times daily. Max: 20 mg 3-4 times daily. Last dos... View More
Oral Children : 0.2 - 0.4 mg/kg every 4 - 8 hours daily. Rectal Child: <12 yr >15 kg: 30 mg bid; >12 yr >35 kg: 60 mg bid.
Renal impairment: Mild to moderate: No dosage adjustment needed. Severe: Reduce dosing to 1-2 times daily w/ prolonged treatment.
Hypersensitivity. GI haemorrhage, obstruction and perforation, patients with prolactin releasing pituitary hormone, chronic admin or routine prophylaxis... View More
Mode of Action
Domperidone is a peripheral dopamine-receptor blocker. It increases oesophageal peristalsis, enhances gastroduodenal coordination and lowers oesophageal... View More
Phaeochromocytoma; children<2 yr, elderly; renal or hepatic impairment. Risk of cardiac arrhythmias and hypokalaemia if administered IV. Pregnancy and l... View More
Drowsiness, extrapyramidal reactions, galactorrhoea, gynaecomastia; constipation or diarrhoea, lassitude, decreased libido, skin rash, itch. Potentia... View More
May antagonise the hypoprolactinaemic effect of bromocriptine. May antagonise the prokinetic effect w/ opioid analgesics and antimuscarinics. Potenti... View More