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Opsonin Pharma Limited
Generic: Methyldopa
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descriptionSafety Advices
Caution is advised when consuming alcohol with Dopamet. Please consult your doctor.
Dopamet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there... View More
Dopamet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not ha... View More
Dopamet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Dopamet should be used with caution in patients with kidney disease. Dose adjustment of Dopamet may be needed. Please consult your doctor. Regular blood... View More
Dopamet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
descriptionMedical Overview


Dopamet is a medicine used in the treatment of high blood pressure (hypertension). Lowering the blood pressure helps prevent future heart attack and str... View More

Uses of Dopamet

  • Hypertension (high blood pressure)

Side effects of Dopamet

  • Dizziness
  • Fatigue
  • Sleepiness
  • Dryness in mouth
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)

How to use Dopamet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Dopamet may be taken with ... View More

How Dopamet works

Dopamet is an alpha-2 agonist. It works by relaxing blood vessels which makes the heart more efficient at pumping blood around the body.

What if you forget to take Dopamet?

If you miss a dose of Dopamet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your r... View More

quick tipsQuick Tips
  • For best results, take Dopamet at the same time every day. Take last dose of the day at bedtime.
  • May cause dizziness and lightheadedness. If this happens to you, do not drive or use machinery.
  • Your doctor may monitor liver function. Inform your doctor if you notice yellowing of the skin or whites of the eyes, abdominal pain, nausea and vomiti... View More
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
  • Do not discontinue use without consulting your doctor even if you feel better.
descriptionBrief Description




May be taken with or without food.

Adult Dose

Oral Hypertension Adult: Monotherapy: Initially, 250 mg bid-tid for 2 days; adjust at intervals of at least 2 days according to response. Maintenance:... View More

Child Dose

Oral Hypertension Child: <12 yr Initially, 10 mg/kg or 300 mg/m2 daily in 2-4 divided doses; adjust at intervals of at least 2 days according to respo... View More

Renal Dose

Renal Impairment Adjust dosage frequency with renal impairment CrCl >50 mL/min: q8hr CrCl 10-50 mL/min: q8-12hr CrCl <10 mL/min: q12-24hr


Active liver disease (e.g. acute hepatitis, active cirrhosis) or depression. Concomitant use w/ MAOIs.

Mode of Action

Methyldopa stimulates alpha 2-adrenoceptors which results in reduced sympathetic tone and fall in BP.


Patient w/ history of haemolytic anaemia, liver disease or depression; parkinsonism, hepatic porphyria. Not intended for the treatment of phaeochromocyt... View More

Side Effect

Drowsiness, orthostatic hypotension, nausea, headache, weakness, fatigue, decreased libido, impotence, impaired concentration and memory, mild psychoses... View More


Reduced hypotensive effects with phenothiazines, TCAs and possibly, amphetamines. Additive hypotensive effects with levodopa; psychosis may also occur. ... View More


The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More

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