Doripen is an antibiotic belonging to the carbapenem group that fights bacteria. It is used to treat severe infections of the skin, lungs, stomach, urin... View More
Uses of Doripen
Side effects of Doripen
How to use Doripen
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Doripen works
Doripen is an antibiotic. It kills bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for them to su... View More
What if you forget to take Doripen?
If you miss a dose of Doripen, please consult your doctor.
Intra-abdominal infections, Bacterial infections, Septicemia, Nosocomial pneumonia, Urinary tract infections, Pyelonephritis
Reconstitution: Reconstitute 500 mg vial w/ 10 mL of sterile water for inj or NaCl 0.9% inj to form a susp containing 50 mg/mL. Further dilute the rec... View More
Intravenous Complicated intra-abdominal infections Adult: 500 mg 8 hrly infused over 1 hr for 5-14 days. May switch to an appropriate oral therapy, af... View More
<18 years: Safety and efficacy not established
Renal impairment: CrCl (ml/min) 30-50 250 mg every 8 hr by IV infusion over 1 hr 11-29 250 mg every 12 hr by IV infusion over 1 hr
Hypersensitivity; anaphylactic reactions to beta-lactams.
Mode of Action
Doripenem is a broad-spectrum carbapenem with potent in vitro antibacterial activity against aerobic and anaerobic gram-positive and gram-negative bacte... View More
May decrease serum concentration of valproic acid to below therapeutic range thus increasing risk of breakthrough seizure; consider alternative antimicr... View More
>10% Headache (4-16%),Nausea (4-12%),Diarrhea (6-11%) 1-10% Anemia (2-10%),Phlebitis (4-8%),Rash (1-5%),Pruritus (3%),Transaminases elevated (1-2%)... View More
Pregnancy Category Note
Pregnancy Category: B Lactation: unknown if excreted in breast milk; use caution
Increased plasma concentration w/ probenecid. May decrease plasma levels of valproic acid thus, increasing the risk of seizures.
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More