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Eluxan 100100mg

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Ziska Pharmaceuticals Ltd.
Generic: Eluxadoline
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descriptionMedical Overview


Indicated for diarrhea-predominant, irritable bowel syndrome (IBS-D), in adult men and women


May be taken with food.

Adult Dose

Irritable Bowel Syndrome Indicated for diarrhea-predominant irritable bowel syndrome (IBS-D) in adult men and women 100 mg PO BID with food Discont... View More


Documented hypersensitivity to drug or components of the formulation Patients who do not have a gallbladder Known or suspected gallbladder obstruc... View More

Mode of Action

Mu opioid receptor agonist; it also is a delta opioid receptor antagonist and a kappa opioid receptor agonist The multiple opioid activity is designe... View More


Eluxadoline is a mu opioid receptor agonist; because of this mechanism of action, the potential for increased risk of sphincter of Oddi spasm exists, re... View More

Side Effect

1-10% Constipation (7-8%) Nausea (7-8%) Abdominal pain (6-7%) URT infection (3-5%) Vomiting (4%) Nasopharyngitis (3-4%) Abdominal distention (3%)... View More

Pregnancy Category Note

Pregnancy No studies in pregnant women Animal reproduction studies Oral and SC administration of eluxadoline to rats and rabbits during organogenes... View More


The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More

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