Eluxan 100100mg

Indication

Indicated for diarrhea-predominant, irritable bowel syndrome (IBS-D), in adult men and women

Administration

May be taken with food.

Adult Dose

Irritable Bowel Syndrome Indicated for diarrhea-predominant irritable bowel syndrome (IBS-D) in adult men and women 100 mg PO BID with food Discont... View More

Contraindication

Documented hypersensitivity to drug or components of the formulation Patients who do not have a gallbladder Known or suspected gallbladder obstruc... View More

Mode of Action

Mu opioid receptor agonist; it also is a delta opioid receptor antagonist and a kappa opioid receptor agonist The multiple opioid activity is designe... View More

Precaution

Eluxadoline is a mu opioid receptor agonist; because of this mechanism of action, the potential for increased risk of sphincter of Oddi spasm exists, re... View More

Side Effect

1-10% Constipation (7-8%) Nausea (7-8%) Abdominal pain (6-7%) URT infection (3-5%) Vomiting (4%) Nasopharyngitis (3-4%) Abdominal distention (3%)... View More

Pregnancy Category Note

Pregnancy No studies in pregnant women Animal reproduction studies Oral and SC administration of eluxadoline to rats and rabbits during organogenes... View More