Ziska Pharmaceuticals Ltd.
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Indicated for diarrhea-predominant, irritable bowel syndrome (IBS-D), in adult men and women
May be taken with food.
Irritable Bowel Syndrome Indicated for diarrhea-predominant irritable bowel syndrome (IBS-D) in adult men and women 100 mg PO BID with food Discont... View More
Documented hypersensitivity to drug or components of the formulation Patients who do not have a gallbladder Known or suspected gallbladder obstruc... View More
Mode of Action
Mu opioid receptor agonist; it also is a delta opioid receptor antagonist and a kappa opioid receptor agonist The multiple opioid activity is designe... View More
Eluxadoline is a mu opioid receptor agonist; because of this mechanism of action, the potential for increased risk of sphincter of Oddi spasm exists, re... View More
1-10% Constipation (7-8%) Nausea (7-8%) Abdominal pain (6-7%) URT infection (3-5%) Vomiting (4%) Nasopharyngitis (3-4%) Abdominal distention (3%)... View More
Pregnancy Category Note
Pregnancy No studies in pregnant women Animal reproduction studies Oral and SC administration of eluxadoline to rats and rabbits during organogenes... View More
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More