Empaglif 25 is used alone or in combination with other medicines to treat type 2 diabetes mellitus. It helps control the high blood sugar levels seen in... View More
Uses of Empaglif 25
Side effects of Empaglif 25
How to use Empaglif 25
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Empaglif 25 may be taken w... View More
How Empaglif 25 works
Empaglif 25 is an antidiabetic medication. It works by removing excess sugar from your body through urine.
What if you forget to take Empaglif 25?
If you miss a dose of Empaglif 25, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to yo... View More
Type 2 diabetes mellitus
May be taken with or without food.
Oral Type 2 diabetes mellitus Adult: Initially, 10 mg once daily in the morning, may be increased to 25 mg once daily, if necessary for additional gl... View More
CrCl (mL/min) <45 Contraindicated. <60 Max: 10 mg daily.
As treatment for type 1 DM or diabetic ketoacidosis. Renal impairment (CrCl <45 mL/min), ESRD, or patients on haemodialysis. Lactation.
Mode of Action
Empagliflozin is a reversible inhibitor of sodium-glucose co-transporter 2 (SGLT2), the main site of filtered glucose re-absorption in the renal proxima... View More
Hypotension: Before initiating Empagliflozin, volume status should be assessed and correction on hypovolemia should be made in the elderly, in patients ... View More
1-10% Urinary tract infection (7.6-9.3%) Female genital mycotic infections (5.4-6.4%) Upper respiratory tract infection (3.1-4%) Increased urination... View More
Pregnancy Category Note
Pregnancy Based on animal data showing adverse renal effects, use not recommended during the second and third trimesters of pregnancy Limited data a... View More
Additive hypoglycaemic effect if concomitantly used w/ insulin and insulin secretagogues (e.g. sulfonylureas). Increased risk of dehydration and hypoten... View More