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Enviral0.25mg/5ml

Oral Solution
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Opsonin Pharma Limited
Generic: Entecavir
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descriptionSafety Advices
AlcoholAlcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Enviral. Please consult your doctor.
PregnancyPregnancy
CONSULT YOUR DOCTOR
Enviral may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing... View More
BreastfeedingBreastfeeding
CONSULT YOUR DOCTOR
Enviral is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
DrivingDriving
UNSAFE
Enviral may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
KidneyKidney
CAUTION
Enviral should be used with caution in patients with kidney disease. Dose adjustment of Enviral may be needed. Please consult your doctor.
LiverLiver
SAFE IF PRESCRIBED
Enviral is safe to use in patients with liver disease. No dose adjustment of Enviral is recommended.
descriptionMedical Overview

Introduction

Enviral is used in the treatment of HIV infection and chronic hepatitis B virus (HBV) infection. It prevents the multiplication of virus in human cells.... View More

Uses of Enviral

  • Chronic hepatitis B virus (HBV) infection

Side effects of Enviral

Common
  • Headache
  • Dizziness
  • Tiredness
  • Nausea

How to use Enviral

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Enviral is to be taken emp... View More

How Enviral works

Enviral is an antiviral medication. It prevents the multiplication of virus in human cells. This stops the virus from producing new viruses and clears u... View More

What if you forget to take Enviral?

If you miss a dose of Enviral, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your r... View More

quick tipsQuick Tips
  • You have been prescribed Enviral for the treatment of chronic hepatitis B virus (HBV) infection.
  • Take it on an empty stomach, at least 2 hours after or before a meal.
  • Enviral may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
  • You may still develop infections or other illnesses associated with viral infection while taking this medication.
  • During treatment and for at least six months after stopping this medicine, regular blood tests are needed to monitor your liver function, level of hepat... View More
descriptionBrief Description

Indication

Chronic hepatitis B

Administration

Should be taken on an empty stomach. Take at least 2 hr after a meal & 2 hr before the next meal. Use oral solution when needed for renal impairment dos... View More

Adult Dose

Chronic Hepatitis B Indicated for treatment of CHB with evidence of active viral replication and either evidence of persistent elevations in serum amin... View More

Child Dose

Chronic Hepatitis B Indicated for treatment of CHB with evidence of active viral replication and either evidence of persistent elevations in serum amin... View More

Renal Dose

Renal Impairment Usual daily dose (0.5 mg) CrCl ?50 mL/min: No dosage adjustment required CrCl 30-49 mL/min: Reduce to 0.25 mg/day or 0.5 mg q48hr C... View More

Contraindication

Entecavir is contraindicated in patients with previously demonstrated hypersensitivity to Entecavir or any component of the product.

Mode of Action

Selective HBV DNA polymerase inhibitor; inhibition blocks reverse transcriptase activity, which in turn reduces viral DNA synthesis

Precaution

Lactic acidosis: Lactic acidosis and severe hepatomegaly with steatosis, including fatal cases have been reported with the use of nucleoside analogues a... View More

Side Effect

1-10% Fatigue (1-3%),Headache (2-4%),Dizziness,Nausea <1% Diarrhea,Dyspepsia,Vomiting,Somnolence,Insomnia

Pregnancy Category Note

Pregnancy Prospective pregnancy data from the APR are not sufficient to adequately assess the risk of birth defects, miscarriage or adverse maternal or... View More

Interaction

Drugs that reduce renal function or compete for active tubular secretion may increase serum conc of either entecavir or co-administered drug.

descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More