Extals 5050mg
Tablet
Unimed Unihealth Pharmaceuticals Ltd.
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| Alcohol | CAUTION Caution is advised when consuming alcohol with Extals 50. Please consult your doctor. |
| Pregnancy | CONSULT YOUR DOCTOR Extals 50 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developi... View More |
| Breastfeeding | CONSULT YOUR DOCTOR Extals 50 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. |
| Driving | UNSAFE Extals 50 may cause side effects which could affect your ability to drive.
You may feel dizzy or light headed after taking this medicine. This may affec... View More |
| Kidney | CONSULT YOUR DOCTOR There is limited information available on the use of Extals 50 in patients with kidney disease. Please consult your doctor. |
| Liver | CONSULT YOUR DOCTOR There is limited information available on the use of Extals 50 in patients with liver disease. Please consult your doctor. |
Introduction
Extals 50 is a prescription medicine used in the treatment of amyotrophic lateral sclerosis (ALS), a degenerative disease that weakens muscles and hence... View More
Uses of Extals 50
- Amyotrophic lateral sclerosis (ALS)
Side effects of Extals 50
- Weakness
- Headache
- Dizziness
- Nausea
- Abdominal pain
- Diarrhea
- Decreased pulmonary function
- Paresthesia (tingling or pricking sensation)
- Sleepiness
- Increased heart rate
- Vomiting
- Pain
- Abnormal liver function tests
How to use Extals 50
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Extals 50 is to be taken e... View More
How Extals 50 works
Extals 50 is a glutamate antagonist and used an an anticonvulsant (anti fits). It is believed to work by inhibiting the action of glutamate (chemical me... View More
- Take it twice a day, 1 hour before or 2 hours after the meal, preferably at the same time.
- It may cause sleepiness. Don't drive or do anything requiring concentration until you know how it affects you.
- Avoid smoking as it may make Extals 50 less effective.
- Your doctor may monitor your liver function, lung function and blood count while you are taking this medicine. Inform your doctor if you develop yellowi... View More
- Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Indication
Amyotrophic lateral sclerosis
Administration
Should be taken on an empty stomach. Take on an empty stomach at least 1 hr before or 2 hr after meals.
Adult Dose
Oral Amyotrophic lateral sclerosis Adult: 50 mg bid. Discontinue if ALT levels increase to 5 times the upper limit of normal (ULN). Hepatic impairm... View More
Contraindication
Hepatic impairment (baseline transaminases >3 times the upper limit of normal).
Mode of Action
Riluzole is a glutamate inhibitor used to slow disease progression and prolong survival rate in patients with amyotrophic lateral sclerosis. The exact m... View More
Precaution
Patient with history of liver diseases. Pregnancy and lactation. Patient Counselling This drug may cause dizziness, drowsiness or vertigo, if affected, ... View More
Side Effect
>10% Oral hypoesthesia (29%) Asthenia (19%) Nausea (16%) 1-10% Decreased lung function (10%) Hypertension (5%) Abdominal pain (5%) Vomiting ... View More
Pregnancy Category Note
Pregnancy There are no studies in pregnant women, and case reports have been inadequate to inform of drug-associated risk Unknown if risk of major b... View More
Interaction
Decreased rate of elimination with CYP1A2 inhibitors (e.g. caffeine, ciprofloxacin, oral contraceptives). Increased rate of elimination with CYP1A2 indu... View More
Alternative brand for Extals 50
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More