Introduction
Alsium belongs to a class of medicines known as benzodiazepines. It is a prescription medicine used to treat epilepsy (seizures) and severe anxiety. It ... View More
Uses of Alsium
Side effects of Alsium
How to use Alsium
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Alsium may be taken with o... View More
How Alsium works
Alsium is a benzodiazepine. It works by increasing the action of a chemical messenger (GABA) which suppresses the abnormal and excessive activity of the... View More
Indication
Anxiety, tension, irritability, restlessness, epilepsy.
Administration
May be taken with or without food. Individualize weight-based dose according to clinical efficacy and tolerability Doses above 5 mg/day should be ... View More
Adult Dose
Seizures Indicated for the adjunctive treatment of seizures associated with Lennox-Gastaut syndrome (LGS) in patients aged 2 years or older >30 kg: In... View More
Child Dose
Seizures Indicated for the adjunctive treatment of seizures associated with Lennox-Gastaut syndrome (LGS) in patients aged 2 years or older <30 kg St... View More
Renal Dose
Renal impairment Mild or moderate renal impairment: No dose adjustment required Severe renal impairment or ESRD: No experience
Contraindication
Hypersensitivity; history of drug dependence; myasthaenia gravis; pregnancy (1st trimester), lactation; serious liver damage; sleep apnoea syndrome; imp... View More
Mode of Action
Clobazam binds to one or more specific GABA receptors at several sites within the CNS including the limbic system and reticular formation. Increased per... View More
Precaution
May impair ability to perform skilled tasks and hazardous activities; elderly; renal or hepatic impairment; alcoholics; obesity; withdrawal should be gr... View More
Side Effect
>10% Somnolence or sedation (26%),Somnolence (22%),Pyrexia (13%),Upper respiratory tract infection (12%) 1-10% Drooling (9%),Aggression (8%),Irrita... View More
Pregnancy Category Note
Pregnancy There are no adequate and well-controlled studies in pregnant women; available data suggest that the class of benzodiazepines is not associat... View More
Interaction
Increased hepatic clearance of clobazam when administered with phenytoin, phenobarbital or carbamazepine. Cimetidine may increase levels of clobazam. ... View More
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More