Glyza 5 is a medicine used to treat type 2 diabetes mellitus. It is used together with a healthy diet and regular exercise to control blood sugar levels... View More
Uses of Glyza 5
Side effects of Glyza 5
How to use Glyza 5
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Glyza 5 may be taken with ... View More
How Glyza 5 works
Glyza 5 is an antidiabetic medication. It works by increasing the release of insulin from the pancreas and decreasing the hormones that raise blood suga... View More
What if you forget to take Glyza 5?
If you miss a dose of Glyza 5, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your r... View More
Type 2 diabetes
May be taken with or without food.
Oral Type 2 diabetes mellitus Adult: 2.5 or 5 mg once daily. Combination therapy: May need to reduce dosage of sulfonylurea or other insulin secreta... View More
<18 years: Safety and efficacy not established
Renal impairment CrCl >50 mL/min: No dose adjustment required CrCl <50 mL/min: Not to exceed 2.5 mg PO qDay ESRD requiring hemodialysis: Not to excee... View More
Documented hypersensitivity (eg, anaphylaxis, angioedema, exfoliative skin conditions)
Mode of Action
Dipeptidyl peptidase IV (DPP-4) inhibition that results in increased incretin hormones and enhanced glycemic control.
Renal impairment Decrease dose with strong CYP450 3A4/5 inhibitors Coadministration with thiazolidinediones (eg, rosiglitazone, pioglitazone) increase... View More
1-10% (selected) Urinary tract infection (7%),Headache (7%),Hypersensitivity-related events (<4%; eg, urticaria, facial edema),Peripheral edema (<4%; i... View More
Strong CYP3A4/5 inhibitors (eg ketoconazole, atazanavir, clarithromycin, indinavir, itraconazole, nefazodone, nelfinavir, ritonavir, saquinavir & telith... View More