Hipre5mg
Tablet
Pacific Pharmaceuticals Ltd.
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| Alcohol | CAUTION Caution is advised when consuming alcohol with Hipre. Please consult your doctor. |
| Pregnancy | CONSULT YOUR DOCTOR Hipre may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing b... View More |
| Breastfeeding | SAFE IF PRESCRIBED Hipre is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. |
| Driving | UNSAFE Hipre may cause side effects which could affect your ability to drive.
Hipre may cause side effects such as dizziness, headaches, nausea or tiredness, a... View More |
| Kidney | SAFE IF PRESCRIBED Hipre is safe to use in patients with kidney disease. No dose adjustment of Hipre is recommended. |
| Liver | CAUTION Hipre should be used with caution in patients with liver disease. Dose adjustment of Hipre may be needed. Please consult your doctor.
Hipre is started a... View More |
Introduction
Hipre belongs to a class of medicines known as a calcium channel blockers. It is used to treat high blood pressure (hypertension) and prevent angina (he... View More
Uses of Hipre
- Hypertension (high blood pressure)
- Angina (heart-related chest pain)
Side effects of Hipre
- Fatigue
- Ankle swelling
- Sleepiness
- Flushing (sense of warmth in the face, ears, neck and trunk)
- Headache
- Nausea
- Dizziness
- Palpitations
- Edema (swelling)
- Abdominal pain
How to use Hipre
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Hipre may be taken with or... View More
How Hipre works
Hipre is a calcium channel blocker. In high blood pressure, it normalizes the blood pressure by relaxing the blood vessels to reduce the pressure on the... View More
What if you forget to take Hipre?
If you miss a dose of Hipre, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your reg... View More
- Take it at the same time every day to help you remember to take it.
- A sudden drop in your blood pressure may occur, especially when you first start taking Hipre. To lower the chance of feeling dizzy or passing out, rise ... View More
- It can cause ankle or foot swelling. To reduce the swelling, raise your legs while you are sitting down. Talk to your doctor if it does not go away.
- It may cause dizziness. Do not drive or perform any activity that requires mental focus until you know how Hipre affects you.
- Inform your doctor if you are pregnant, planning a pregnancy or breastfeeding.
Indication
Oral Prinzmetal's angina; Stable angina Adult: Initially, 5 mg once daily increased to 10 mg once daily if necessary. Elderly: Initially, 2.5 mg once... View More
Administration
Plasma concentrations may be elevated w/ CYP3A4 inhibitors (e.g. azole antifungals, ritonavir). Concomitant therapy w/ simvastatin may increase risk of ... View More
Adult Dose
Impaired liver or renal function, CHF, sick-sinus syndrome, severe ventricular dysfunction, hypertrophic cardiomyopathy, severe aortic stenosis. Caution... View More
Renal Dose
Amlodipine relaxes peripheral and coronary vascular smooth muscle. It produces coronary vasodilation by inhibiting the entry of Ca ions into the slow ch... View More
Contraindication
Hypertension <6 years: Safety and efficacy not established >6 years: 2.5-5 mg/day PO
Mode of Action
May be taken with or without food.
Precaution
Mild to moderate hypertension, Chronic stable and vasospastic angina, Raynaud's disease, Coronary Artery Disease, HTN, Stroke prevention
Pregnancy Category Note
>10% Edema (1.8-10.8%),Pulmonary edema (7-15%) 1-10% Headache (7.3%),Fatigue (4.5%),Palpitations (0.7-4.5%),Dizziness (1.1-3.4%),Nausea (2.9%),Flus... View More
Interaction
Hypersensitivity to Amlodipine or other calcium channel antagonist, Severe hypertension.
Alternative brand for Hipre
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More