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Drug International Ltd.
Generic: Sofosbuvir
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descriptionSafety Advices
It is not known whether it is safe to consume alcohol with HopSo. Please consult your doctor.
HopSo is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there a... View More
HopSo is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
HopSo may cause side effects which could affect your ability to drive. HopSo, when taken together with other medicines for the treatment of hepatitis c ... View More
HopSo should be used with caution in patients with severe kidney disease. Dose adjustment of HopSo may be needed. Please consult your doctor. Limited in... View More
HopSo is safe to use in patients with liver disease. No dose adjustment of HopSo is recommended.
descriptionMedical Overview


HopSo is an antiviral medication. It is used along with other medications for the treatment of chronic hepatitis C virus (HCV) infection. It works by lo... View More

Uses of HopSo

  • Chronic hepatitis C virus (HCV) infection

Side effects of HopSo

  • Fatigue
  • Nausea
  • Headache
  • Insomnia (difficulty in sleeping)
  • Anemia (low number of red blood cells)

How to use HopSo

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. HopSo is to be taken with ... View More

How HopSo works

HopSo is an antiviral medication. It works by lowering a load of hepatitis C virus in the body and removing the virus from the blood over a period of ti... View More

What if you forget to take HopSo?

If you miss a dose of HopSo, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your reg... View More

quick tipsQuick Tips
  • HopSo is used along with other medications for the treatment of chronic hepatitis C virus (HCV) infection.
  • Do not skip any doses and finish the full course of treatment even if you feel better.
  • It has fewer side effects compared to other similar medications.
  • Take it with food, preferably at the same time everyday.
  • You will usually need to take this medicine every day for either 12 or 24 weeks.
  • It may cause fatigue, dizziness, and blurred vision. Don't drive or do anything requiring concentration until you know how it affects you.
  • Your doctor may monitor your liver function and the amount of hepatitis C virus in your body regularly.
  • Do not stop taking HopSo without your doctor's advice.
descriptionBrief Description


Chronic Hepatitis C, Patients with hepatocellular carcinoma awaiting liver transplantation


Should be taken with food.

Adult Dose

Oral Chronic Hepatitis C One 400 mg tablet taken once daily with or without food - Should be used in combination with Ribavirin or in combination wit... View More

Child Dose

Safety and efficacy not established


When Sofosbivur is used in combination with Ribavirin or Peginterferon alfa/Ribavirin, the contraindications applicable to those agents are applicable t... View More

Mode of Action

Nucleotide prodrug that undergoes metabolism to the active uridine analog triphosphate, an inhibitor of HCV NS5B RNA-dependent polymerase; its inhibitio... View More


Pregnancy: Ribavirin may cause birth defects and fetal death and animal studies have shown interferons have abortifacient effects; avoid pregnancy in fe... View More

Side Effect

>10% Sofosbuvir plus ribavarin (12 weeks) Fatigue (38%),Headache (24%),Nausea (22%),Insomnia (15%),Pruritus (11%),Sofosbuvir plus ribavarin (24 weeks)... View More

Pregnancy Category Note

Pregnancy Category: B; Category X when used in combination with ribavirin or peginterferon alfa/ribavirin


Reduced therapeutic effect w/ drugs that are potent P-gp inducers in the intestine (eg rifampicin, St. John's wort, carbamazepine & phenytoin), modafini... View More

Alternative brand for HopSo
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More

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