Incrit 100 is a medicine used to treat type 2 diabetes mellitus. It is used together with a healthy diet and regular exercise to control blood sugar lev... View More
Uses of Incrit 100
Side effects of Incrit 100
How to use Incrit 100
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Incrit 100 may be taken wi... View More
How Incrit 100 works
Incrit 100 is an antidiabetic medication. It works by increasing the release of insulin from the pancreas and decreasing the hormones that raise blood s... View More
What if you forget to take Incrit 100?
If you miss a dose of Incrit 100, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to you... View More
Type 2 diabetes mellitus
May be taken with or without food.
Oral Type 2 diabetes mellitus Adult: 100 mg once daily. Hepatic impairment Mild to moderate impairment: Dose adjustment not necessary Severe impa... View More
Safety and efficacy not established
Renal impairment CrCl >50 mL/min: Dose adjustment not necessary CrCl 30-50 mL/min: 50 mg PO qDay CrCl <30 mL/min: 25 mg PO qDay ESRD: 25 mg PO qDay ... View More
Hypersensitivity reactions such as anaphylaxis, angioedema, and exfoliative skin conditions including Stevens-Johnson syndrome can occur. Type 1 diabete... View More
Mode of Action
Sitagliptin inhibits dipeptidyl peptidase IV (DPP-IV), resulting in prolonged active incretin levels. Incretin hormones increases insulin synthesis and ... View More
Patient w/ type 1 diabetes, history of angioedema. Not intended for the treatment of diabetic ketoacidosis. Moderate and severe renal impairment. Pregna... View More
1-10% Nasopharyngitis (5%),Diarrhea (4%),Headache (3.6%),Constipation (3%),Peripheral edema (2%),Nausea (2%),Pharyngitis (1%),Osteoarthritis (1%),URI (... View More
Increased risk of hypoglycaemia when used in combination w/ sulfonylureas or insulin.