Introduction
Accolate is a prescription medicine used for asthma prevention and for the treatment of allergy symptoms such as sneezing and runny nose. It reduces inf... View More
Uses of Accolate
Side effects of Accolate
How to use Accolate
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Accolate is to be taken em... View More
How Accolate works
Accolate works by blocking the action of leukotriene. It lowers inflammation in the airways and nose to prevent asthma.
What if you forget to take Accolate?
If you miss a dose of Accolate, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your ... View More
Indication
Chronic asthma
Administration
Should be taken on an empty stomach. Take at least 1 hr before or 2 hr after meals.
Adult Dose
Oral Chronic asthma Adult: 20 mg bid. Hepatic impairment: Contraindicated.
Child Dose
Oral Chronic asthma Child: 5-11 yr: 10 mg bid. >12 yr: 20 mg bid.
Renal Dose
Renal Impairment Dose adjustment not necessary
Contraindication
Hypersensitivity, hepatic impairment, cirrhosis, acute asthmatic attacks. Lactation.
Mode of Action
Zafirlukast selectively antagonises the leukotriene D4 receptor. It inhibits bronchoconstriction caused by various inhaled antigens or irritants. It is ... View More
Precaution
Not indicated for use in the reversal of bronchospasm in acute asthma attacks. Avoid abrupt substitution to oral or inhaled corticosteroids. Renal impai... View More
Side Effect
>10% headache (12.9% in age >12 yr) 1-10% Abdominal pain (1.8%),Infection (3.5%),Nausea (3.1%),Diarrhea (2.8%),Generalized pain (1.8%),Vomiting (1.... View More
Interaction
May enhance anticoagulant activity of warfarin resulting to increased prothrombin time. Decreased plasma levels w/ theophylline, terfenadine and erythro... View More
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More