Isotretinion20mg
Capsule
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| Alcohol | CAUTION Caution is advised when consuming alcohol with Isotretinion. Please consult your doctor. |
| Pregnancy | UNSAFE Isotretinion is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful... View More |
| Breastfeeding | CONSULT YOUR DOCTOR Isotretinion is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. |
| Driving | UNSAFE Isotretinion may cause side effects which could affect your ability to drive.
Your night vision may get worse during your treatment. This can happen sud... View More |
| Kidney | SAFE IF PRESCRIBED Isotretinion is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Isotretinion may not be ne... View More |
| Liver | UNSAFE Isotretinion is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor. |
Introduction
Isotretinion belongs to a group of medicines called retinoids, which are closely related to vitamin A derivative. It is used to treat severe acne that h... View More
Uses of Isotretinion
- Acne
Side effects of Isotretinion
- Dry skin
How to use Isotretinion
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Isotretinion is to be take... View More
How Isotretinion works
Isotretinion is a derivative of vitamin A. It acts on glands (sebaceous) to reduce the production of a natural substance (sebum) that causes acne. Also,... View More
What if you forget to take Isotretinion?
If you miss a dose of Isotretinion, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to y... View More
- Take it with food.
- Avoid exposure to sunlight while using Isotretinion. Use protective measures such as sun-cream or protective clothing.
- Avoid face waxing and laser treatment while using this medicine as it makes your skin more fragile.
- Avoid taking tetracycline as it may reduce the Isotretinion activity.
- Do not take Isotretinion if you are pregnant, planning pregnancy or breastfeeding.
- It may cause dryness of mouth, lips, and eyes. Drink plenty of water, use moisturiser and avoid wearing contact lenses. Inform your doctor if it bothers... View More
Indication
Acne
Administration
Should be taken with food.
Adult Dose
Oral Severe, Recalcitrant Nodular Acne Severe nodular acne unresponsive to conventional therapy, including systemic antibiotics Adult: 0.5-1 mg/kg/da... View More
Child Dose
Severe, Recalcitrant Nodular Acne Severe nodular acne unresponsive to conventional therapy, including systemic antibiotics <12 years: Safety and effic... View More
Renal Dose
Renal impairment: Severe: Reduce initial dose (e.g. 10 mg daily), then gradually increase to 1 mg/kg as necessary.
Contraindication
Pregnancy, lactation.
Mode of Action
Isotretinoin is a synthetic retinoid which reduces sebaceous gland size and sebum production. It also regulates cell proliferation and differentiation.
Precaution
Preexisting or predisposition to hypertriglyceridaemia (e.g. DM, obesity or increased alcohol intake). Monitor triglyceride levels. Monitor blood lipids... View More
Side Effect
>10% Cheilitis (90%),Xerosis,Xerostomia,Dry nose,Epistaxis,Pruritus,Conjunctivitis (including blepharoconjunctivitis) (40%),Irritation (40%),Increased ... View More
Interaction
Additive toxicity with vitamin A or its derivatives. Decreased efficacy of microdosed progesterone (use 2 forms of contraception). May increase risk of ... View More
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More