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Linamide 25

Capsule-(25mg)
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Beacon Pharmaceuticals PLC

Generic: Lenalidomide

6 Capsules (1 Strip)
৳ 2181.60
৳ 2400
9% OFF
Alternative Brands For Linamide 25

Medicine Overview of Linamide 25mg Capsule

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Introduction

Linamide 25 is used in the treatment of multiple myeloma and lepra reaction. This medicine belongs to a group of medicines which affect how your immune system works. Linamide 25 can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. Some common side effects of this medicine include headache, weakness, nausea, rash, and dizziness. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections or bleeding. Hence, take caution while performing the activity that might increase your chances of bleeding or avoid contact with people suffering from infection such as cold. Regular blood tests are required to check your blood cells while on treatment. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You are advised to drink plenty of fluids to stay hydrated while taking this medicine.

Uses of Linamide 25

  • Multiple myeloma
  • Lepra reaction

Side effects of Linamide 25

Common
  • Headache
  • Weakness
  • Nausea
  • Rash
  • Dizziness
  • Sleepiness
  • Edema (swelling)
  • Loss of appetite
  • Decreased white blood cell count
  • Decreased calcium level in blood
  • Weight gain
  • Muscle weakness
  • Fatigue
  • Fever
  • Anxiety
  • Blood clots
  • Dry skin
  • Weight loss
  • Confusion
  • Decreased white blood cell count (neutrophils)
  • Neuropathy
  • Constipation
  • Tremor

How to use Linamide 25

Take this medicine in the dose and duration as advised by your doctor. Do not chew, crush or break it. Linamide 25 may be taken with or without food, but it is better to take it at a fixed time.

How Linamide 25 works

Linamide 25 is an anti-cancer medication. It works by enhancing the immune system that indirectly attacks the cancer cells. It prevents the growth of new blood vessels within the tumor. It also restricts the production of chemical messengers (cytokine and growth factor) which are responsible for the growth of cancer cells. This is how it works against cancer.

Quick Tips

  • You may be monitored with regular blood tests before and during the treatment as lenalidomide may cause a fall in the white blood cells and platelets, required to fight infection, Hemoglobin and blood clotting.
  • Avoid activities that may cause bruising or injury and avoid contact with people who have colds or infections.
  • It makes your skin sensitive towards sunlight. Apply sunscreen or wear protective while going out.
  • It may cause dehydration. Drink plenty of water to stay hydrated while taking medication.
  • It is not recommended for use in children and adolescents under 18 years.
  • You should use proper contraceptive methods at least 4 weeks before, during and until 4 weeks after stopping treatment.
  • Woman of childbearing potential will be required to undergo pregnancy tests before and after the treatment.
  • You should inform your doctor or dentist that you are taking Linamide 25 before you receive any medical or dental care, emergency care, or surgery.
  • It may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
  • You may be at risk of developing acute myelogenous leukemia, Hodgkin lymphoma tumor lysis syndrome, fatal liver problems, severe skin reactions, and fatal heart problems during treatment with Linamide 25. You should discuss in advance the benefits and risks of taking this medicine.

Brief Description

Indication

Myelodysplastic disease, Multiple myeloma

Administration

May be taken with or without food. Swallow whole, do not break/chew/open.

Adult Dose

Oral Myelodysplastic disease Adult: Initially, 10 mg once daily for 21 consecutive days of repeated 28-day cycle. Multiple myeloma Adult: In combination w/ dexamethasone. Lenalidomide: Initially, 25 mg once daily for 21 consecutive days of repeated 28-day cycle. Dexamethasone: 40 mg once daily on days 1-4, 9-12 and 17-20 of each 28-day cycle, for the 1st 4 cycles, then 40 mg once daily on days 1-4 of each 28-day cycle. Elderly: No dosage adjustment needed.

Child Dose

<18 years old: Safety and efficacy not established

Renal Dose

Myelodysplastic disease: Moderate: 5 mg once daily. Severe (not requiring dialysis): 5 mg every other day. End-stage renal disease: 5 mg 3 times/wk after dialysis. Multiple myeloma: Moderate: 10 mg once daily may be increased to 15 mg once daily after 2 cycles if needed. Severe (not requiring dialysis): 15 mg every other day, may be increased to 10 mg once daily if needed. End-stage renal disease: 5 mg once daily after dialysis.

Contraindication

Pregnancy and lactation; sexually active women of childbearing potential not using 2 forms of contraception. Demonstrated hypersensitivity (eg, angioedema, Stevens-Johnson syndrome, toxic epidermal necrolysis)

Mode of Action

Lenalidomide, a thalidomide analogue, is an immunomodulatory agent w/ antiangiogenic and antineoplastic property. It inhibits proinflammatory cytokines secretion, increases interleukin-2 and interferon-γ secretion, and increases cytolytic T-cell and natural killer cell response. It also inhibits the growth of myeloma cells by inducing cell cycle arrest and cell death.

Precaution

Potential for human birth defects Analog of thalidomide, a known human teratogen that causes severe, life-threatening human birth defects. Avoid during pregnancy; if taken during pregnancy, likely to cause birth defects or fetal death. Pregnancy test is required prior initiation of therapy and should commence contraceptive measures following negative result. Pregnancy test must be repeated at a regular interval during therapy. History of thrombosis; smokers; patients w/ HTN, hyperlipidaemia, high tumour burden. Renal impairment. Significantly increased risk of deep vein thrombosis (DVT) and pulmonary embolism (PE), as well as risk of myocardial infarction and stroke in patients with multiple myeloma receiving lenalidomide with dexamethasone. Lactation: discontinue drug or do not nurse

Side Effect

>10% Thrombocytopenia (62%),Neutropenia (59%),Diarrhea (48%),Pruritus (42%),Nausea (35%),Rash (35%),Fatigue (31%),Constipation (24%),Arthralgia (22%),Back pain (21%),Peripheral edema (21%),Pyrexia (21%),Dizziness (20%),Headache (20%),Cough (19%),Muscle cramp (18%),Dyspnea (17%),URTI (15%),Anemia (12%),Pneumonia (12%),UTI (11%) 1-10% (critical AEs) Tumor flare reaction - MCL (10%),Abdominal pain (8%),Leukopenia (8%),Myalgia (8%),Pain (7%),Bronchitis (6%),Rhinitis (6%),Febrile neutropenia (5%),Peripheral neuropathy (5%) Potentially Fatal: Stevens-Johnson syndrome, toxic epidermal necrolysis, erythema multiforme, angioedema. Acute hepatic failure; toxic, cytolytic, cholestatic and mixed cytolytic/ cholestatic hepatitis.

Interaction

May increase risk of thrombosis w/ erythropoietic agents. May increase plasma concentration of digoxin, ketoconazole, itraconazole, ciclosporin, verapamil, quinidine, clarithromycin.

Buy Linamide 25 from Arogga

In Bangladesh, you can get the original Linamide 25. Select your favorite one from a large collection of medicine products. Order from App to get more offers and better experience.

What is the price of Linamide 25 in Bangladesh?

The latest price of Linamide 25 in Bangladesh is 2181.6৳. You can buy Linamide 25 at the best price from Arogga. Order online through our website or mobile app and get fast home delivery anywhere in Bangladesh. Cash on Delivery (COD) is available all over Bangladesh.

Frequently Questions & Answers

Is the product authentic?

Yes. Arogga sources all medicines and health products directly from trusted suppliers, distributors, or manufacturers. Every product is verified before delivery.

Does Arogga deliver all over Bangladesh?

Yes, Arogga delivers nationwide. You can order from anywhere in Bangladesh.

Is Cash on Delivery(COD) available?

Yes, Cash on Delivery is available across Bangladesh for most products.

How long does delivery take?

Delivery usually takes 24–48 hours inside Dhaka and 3–5 days outside Dhaka, depending on location and courier load.

Can I return or replace the product?

If the product is damaged, incorrect, or expired, you can request a replacement or refund according to Arogga’s return policy.

Safety Advices

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CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Linamide 25. Please consult your doctor.
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UNSAFE
Linamide 25 is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
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CONSULT YOUR DOCTOR
Linamide 25 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
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UNSAFE
Linamide 25 may cause side effects which could affect your ability to drive. You may feel dizzy, tired, sleepy, have vertigo or blurred vision after taking Linamide 25 and this may affect your ability to drive.
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CAUTION
Linamide 25 should be used with caution in patients with kidney disease. Dose adjustment of Linamide 25 may be needed. Please consult your doctor.
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CAUTION
Linamide 25 should be used with caution in patients with liver disease. Dose adjustment of Linamide 25 may be needed. Please consult your doctor.

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Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.