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Safety Advices
বাংলা
English
SAFE
Consuming alcohol with Lomeflox 400 does not cause any harmful side effects.
CONSULT YOUR DOCTOR
Lomeflox 400 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
CONSULT YOUR DOCTOR
Lomeflox 400 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
SAFE
Lomeflox 400 does not usually affect your ability to drive.
CAUTION
Lomeflox 400 should be used with caution in patients with kidney disease. Dose adjustment of Lomeflox 400 may be needed. Please consult your doctor.
CONSULT YOUR DOCTOR
There is limited information available on the use of Lomeflox 400 in patients with liver disease. Please consult your doctor.
Medicine Overview of Lomeflox 400mg Tablet
Introduction
Lomeflox 400 is an antibiotic, used in the treatment of bacterial infections. It is also used in treating infections of the urinary tract, nose, throat, skin and soft tissues and lungs (pneumonia). It cures the infection by stopping the further growth of the causative microorganisms. Lomeflox 400 should be used in the dose and duration as advised by your doctor. It may be taken with or without food, preferably at a fixed time. Avoid taking antacids containing aluminum or magnesium within 2 hours before or 2 hours after you take this medicine. Taking antacids, sucralfate, or vitamin or mineral supplements...
... Show moreUses of Lomeflox 400
- Bacterial infections
Side effects of Lomeflox 400
Common
- Headache
- Dizziness
- Nausea
- Constipation
- Diarrhea
How to use Lomeflox 400
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lomeflox 400 may be taken with or without food, but it is better to take it at a fixed time.
How Lomeflox 400 works
Lomeflox 400 is an antibiotic medicine to be taken by mouth. It works by stopping the action of a bacterial enzyme called DNA-gyrase. This prevents the bacterial cells from dividing and repairing, thereby killing them.
What if you forget to take Lomeflox 400?
If you miss a dose of Lomeflox 400, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
- Your doctor has prescribed Lomeflox 400 to cure your infection and improve symptoms.
- Do not skip any doses and finish the full course of treatment even if you feel better.
- Discontinue Lomeflox 400 and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.
- Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.
- Notify your doctor if you feel pain in your tendons, numbness, or tingling sensations.
- Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
Brief Description
Indication
Chronic bronchitis, Otitis media, Bacterial Conjunctivitis, Urinary tract infections, Surgical Prophylaxis, Otitis externa
Administration
May be taken with or without food.
Adult Dose
Oral
Acute bacterial exacerbation of chronic bronchitis
Adult: 400 mg once daily for 10 days.
Uncomplicated urinary tract infections
Adult: 400 mg once daily.
Due to E. coli: For 3 successive days.
Due to K. pneumoniae, P. mirabilis or S. saprophyticus: For 10 successive days.
Complicated urinary tract infections
Adult: Due to E. coli, K. pneumoniae, P. mirabilis or P. aeruginosa: 400 mg once daily for 14 successive days.
Prophylaxis of surgical infections
Adult: 400 mg as a single dose 1-6 hr before procedure.
Renal Dose
Renal impairment: Haemodialysis: Initially, 400 mg daily. Maintenance: 200 mg daily.
CrCl (ml/min) Dosage Recommendation
10-40 Initially, 400 mg daily. Maintenance: 200 mg daily.
Contraindication
Hypersensitivity to the drug or other quinolones; children <18 yr; pregnancy and lactation.
Mode of Action
Lomefloxacin promotes breakage of double-stranded DNA in susceptible organisms and inhibits DNA gyrase, which is essential in reproduction of bacterial DNA.
Precaution
Avoid prolonged exposure to sunlight or artificial UV light. Known or suspected CNS disorders e.g. severe cerebral arteriosclerosis, epilepsy or other factors that predispose to seizures. Avoid in patients with known QT prolongation, uncorrected hypokalaemia. May impair ability to drive or operate machinery. Renal impairment.
Side Effect
Nausea, abdominal pain or discomfort, diarrhoea; headache, dizziness, insomnia; rash, pruritus, photosensitivity; thrombocytopenia.
Potentially Fatal: Anaphylactic or anaphylactoid reactions.
Interaction
Reduced bioavailability with sucralfate, antacids containing magnesium or aluminium, vitamin or mineral supplements containing iron. Increased serum levels with cimetidine. Potential increase in serum levels of ciclosporin. Renal elimination reduced with probenecid.
Potentially Fatal: Increased risk of ventricular arrhythmias with class IA (quinidine, procainamide) or class III (amiodarone, sotalol) antiarrhythmic agents.
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