Pregnancy Dexamethasone shown to be teratogenic in mice and rabbits following topical ophthalmic application in multiples of therapeutic dose In mouse, corticosteroids produce fetal resorptions and a specific abnormality, cleft palate; in the rabbit, corticosteroids have produced fetal resorptions and multiple abnormalities involving head, ears, limbs, palate, etc There are no adequate or well-controlled studies in pregnant women; however, prolonged or repeated corticoid use during pregnancy associated with increased risk of intra-uterine growth retardation; neomycin and polymyxin B sulfates and dexamethasone ophthalmic suspension should be used during pregnancy only if potential benefit to mother justifies potential risk to embryo or...