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Megacin

Capsule-(500mg)
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Nevian Lifescience PLCchevron-right

Generic: Cephradine

Stock AvailableStock: Available
1 Capsule
৳12.21
৳13
6% OFF
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Medicine Overview of Megacin 500mg Capsule

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Indication

Pneumonia, Pharyngitis, Susceptible infections, Otitis media, Skin and Skin-Structure Infections, Rheumatic fever, Tonsillitis, Respiratory tract infections, Urinary tract infections, Surgical Prophylaxis, Genitourinary tract infections, Acute prostatitis

Administration

May be taken with or without food. May be taken w/ meals to reduce GI discomfort. Parenteral doses by deep IM or slow IV inj over 3-5 min or by IV infusion. Reconstitution: IM: Add 2 mL or 4 mL of sterile water for inj or NaCl 0.9% inj to 500 mg or 1 g vial, respectively. IV: Add 5 mL of sterile water for inj, dextrose 5% inj, NaCl 0.9% inj or other suitable soln to 500 mg vial. Shake well the entire soln.

Adult Dose

Adult: PO Susceptible infections 1-2 g/day in 2-4 divided doses. Max: 4 g/day. Surgical prophylaxis 1-2 g pre-op. Subsequent doses may be given as needed. Skin and skin structures and respiratory tract infection: Usual dose is 250 mg every 6 hours or 500 mg every 12 hours. Lobar pneumonia: 500 mg every 6 hours or 1 gm every 12 hours. Urinary tract infection: Usual dose is 500 mg every 12 hours. Gastro-intestinal tract infection: 500 mg three to four times daily. IV/IM Severe infections 2-4 g/day in 4 divided doses. Max: 8 g/day.

Child Dose

Children: Oral: The usual total dose is 25 to 50 mg/kg/day given in 2 to 4 equally divided doses. Injection: 50 to 100 mg/kg/day in 4 equally divided doses. The usual total dose may be increased up to 200-300 mg/kg/day. Perioperative prophylaxis: Recommended dose is 1-2 gm by intramuscular or intravenous route; subsequent parenteral or oral doses are given as appropriate.

Renal Dose

Renal impairment: For patients undergoing chronic intermittent haemodialysis: 250 mg may be given at the start of the session, repeated after 6-12 hr, then again 36-48 hr after the initial dose, and again at the start of the next haemodialysis if >30 hr have elapsed since the previous dose. CrCl (ml/min) >20 500 mg every 6 hr. 5-20 250 mg every 6 hr. <5 250 mg every 12 hr.

Contraindication

Hypersensitivity to cefradine or other cephalosporins; porphyria.

Mode of Action

Cefradine is a 1st generation cephalosporin which inhibits the final transpeptidation step of the peptidoglycan synthesis in bacterial cell wall by binding to one or more of the penicillin-binding proteins (PBPs), thus arresting cell wall synthesis leading to bacterial cell death.

Precaution

Renal impairment; history of penicillin sensitivity; pregnancy; lactation.

Side Effect

Diarrhoea, nausea, vomiting; leukopenia, neutropenia, eosinophilia, rash, pruritus; joint pain; increased BUN and creatine; dizziness. Potentially Fatal: Pseudomembranous colitis.

Interaction

Increased risk of nephrotoxicity w/ loop diuretics. Decreased renal clearance w/ probenecid.

Buy Megacin from Arogga

In Bangladesh, you can get the original Megacin. Select your favorite one from a large collection of Medicine products. Order from App to get more offers and better experience.

What is the price of Megacin in Bangladesh?

The latest price of Megacin in Bangladesh is 12.21৳. You can buy Megacin at the best price from Arogga. Order online through our website or mobile app and get fast home delivery anywhere in Bangladesh. Cash on Delivery (COD) is available all over Bangladesh.

Frequently Asked Questions (FAQ)

Is Megacin authentic?

Yes. Arogga sources Megacin products from trusted suppliers, distributors, or manufacturers. Products are verified before delivery.

Does Arogga deliver all over Bangladesh?

Arogga delivers most products across Bangladesh. However, refrigerated or cold-chain medicines are delivered only within Dhaka. Delivery of some other products may also depend on product condition, storage requirements, and delivery location.

Is Cash on Delivery (COD) available for Megacin?

Yes. Cash on Delivery is available for all products in eligible locations across Bangladesh. Availability may vary depending on the product and delivery location.

How long does delivery take?

Delivery usually takes 24–48 hours inside Dhaka and 3–5 days outside Dhaka, depending on product availability, delivery location, and courier load.

Can I return or replace the product?

If the product is damaged, incorrect, or expired, you can request a replacement or refund according to Arogga’s return policy..

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Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.