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Safety Advices
বাংলা
English
UNSAFE
It is unsafe to consume alcohol with Melcam 15.
CONSULT YOUR DOCTOR
Melcam 15 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
SAFE IF PRESCRIBED
Melcam 15 is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
CONSULT YOUR DOCTOR
It is not known whether Melcam 15 alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
CAUTION
Melcam 15 should be used with caution in patients with severe kidney disease. Dose adjustment of Melcam 15 may be needed. Please consult your doctor.
Limited information is available on the use of Melcam 15 in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.
CAUTION
Melcam 15 should be used with caution in patients with severe liver disease. Dose adjustment of Melcam 15 may be needed. Please consult your doctor.
Medicine Overview of Melcam 15mg Tablet
Introduction
Melcam 15 is a pain relieving medicine. It is used for treatment of pain and inflammation in conditions like osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis. It provides relief from pain, swelling, and redness. Melcam 15 can be taken with or without food. The dose and duration will depend on what you are taking it for and how well it helps your symptoms. You should keep taking the medicine even if you feel better until the doctor says it is alright to stop using it. The most common side effects of this medicine include mild headache and dizziness, nausea, abdominal...
... Show moreUses of Melcam 15
- Pain relief
Side effects of Melcam 15
Common
- Vomiting
- Stomach pain
- Nausea
- Indigestion
- Diarrhea
How to use Melcam 15
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Melcam 15 may be taken with or without food, but it is better to take it at a fixed time.
How Melcam 15 works
Melcam 15 is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that are responsible for inflammation (pain and swelling).
What if you forget to take Melcam 15?
If you miss a dose of Melcam 15, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
- Inform your doctor if you have ever been diagnosed with kidney or liver problems.
- It can cause serious complications like stomach bleeding and kidney problems if taken for a long time.
- Melcam 15 can raise your risk of blood clots, heart attack, or a stroke.
- Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
Brief Description
Indication
Rheumatoid arthritis, Osteoarthritis, Ankylosing spondylitis
Administration
May be taken with or without food. May be taken w/ meals if GI discomfort occurs.
Adult Dose
Oral
Rheumatoid arthritis; Ankylosing spondylitis
Adult: 15 mg daily as a single dose. Patients w/ increased risk of adverse effects: Initially, 7.5 mg daily.
Acute exacerbations of osteoarthritis
Adult: 7.5 mg daily up to max 15 mg daily as a single dose.
Elderly: 7.5 mg daily for long-term treatment.
Child Dose
Oral
Juvenile rheumatoid arthritis
Child: >2 yr 0.125 mg/kg once daily. Max: 7.5 mg daily.
Renal Dose
Renal impairment: Mild to moderate: No dosage adjustment needed.
Severe: Not recommended.
Dialysis patient: 7.5 mg daily.
Contraindication
Hypersensitivity to meloxicam, aspirin or other NSAIDs; severe hepatic impairment; bleeding disorders; renal failure without dialysis. Rectal admin in patients with proctitis, haemorrhoids or rectal bleeding.
Mode of Action
Meloxicam is an oxicam derivative which exhibits analgesic, antipyretic and anti-inflammatory actions. It reversibly inhibits the cyclooxygenase-1 and -2 (COX-1 and -2) enzymes, thus resulting in reduced synthesis of prostaglandin precursors.
Precaution
History of GI disease, asthma, hypertension, CVD or risk factors, fluid retention or heart failure. Monitor patients with advanced renal disease. May impair ability to drive or operate machinery. Elderly. Pregnancy (avoid in the 3rd trimester) and lactation.
Side Effect
1-10%
Indigestion (3.8-9.5%),Upper respiratory infection (<8.3%),Headache (2.4-8.3%),Diarrhea (1.9-7.8%),Nausea (2.4-7.2%),Abdominal pain (1.9-4.7%),Edema (0.6-4.5%),Anemia (<4.1%),Dizziness (1.1-3.8%),Constipation (0.8-2.6%),Angina (<2%),Congestive heart failure (<2%),Decreased platelet aggregation, purpuric disorder (<2%),Gastrointestinal (GI) hemorrhage (<2%),GI perforation, GI ulcer (<2%),Hepatitis (<2%),Hypertension (<2%),Inflammatory disorder of digestive tract (<2%),Myocardial infarction (<2%),Vomiting (<3%)
<1%
Anaphylactoid reaction,Angioedema,Fever,Asthma, bronchospasm,Cerebrovascular accident,Erythema multiforme, erythroderma,Immune hypersensitivity reaction,Interstitial nephritis, renal failure,Jaundice, liver failure,Stevens-Johnson syndrome,Tinnitus, hearing loss,Toxic epidermal necrolysis
Potentially Fatal: Stevens Johnson syndrome, thrombocytopenia, interstitial nephritis and idiosyncratic liver abnormality.
Pregnancy Category Note
Pregnancy category: C; D in third trimester of pregnancy; drug should be avoided in late pregnancy
Interaction
Increased risk of severe GI effects w/ aspirin or warfarin. May antagonise antihypertensive effects of ACE inhibitors and angiotensin II receptor antagonists. May reduce natriuretic effects of furosemide and thiazides. Enhanced toxicity of methotrexate. May increase plasma lithium concentration.
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