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Menoral
Square Pharmaceuticals PLC.
Generic: Norethisterone
Safety Advices
বাংলা
English
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Menoral. Please consult your doctor.
UNSAFE
Menoral is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
CONSULT YOUR DOCTOR
Menoral is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Nonhormonal contraceptives are preferred in breastfeeding women, especially during the first 4 weeks postpartum
UNSAFE
Menoral may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
CONSULT YOUR DOCTOR
There is limited information available on the use of Menoral in patients with kidney disease. Please consult your doctor.
CAUTION
Menoral should be used with caution in patients with liver disease. Dose adjustment of Menoral may be needed. Please consult your doctor.
Use of Menoral is not recommended in patients with severe liver disease. Inform your doctor if you develop signs of jaundice like yellowing of eyes and skin, itching, and clay colored stools.
Medicine Overview of Menoral 5mg Tablet
Introduction
Menoral is used to treat various menstrual problems including painful, heavy, or irregular periods, premenstrual syndrome (PMS) and a condition called endometriosis. It is a man-made version of the natural female sex hormone progesterone. Menoral may be taken with or without food, but it is better to take it at the same time each day. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need so as to improve your symptoms. Swallow the tablets whole with a drink of water. You should take this medicine for...
... Show moreUses of Menoral
- Pain during menstruation
- Endometriosis
- Heavy menstrual bleeding
Side effects of Menoral
Common
- Headache
- Dizziness
- Breast tenderness
- Nausea
- Vaginal spotting
- Vomiting
- Abdominal cramp
How to use Menoral
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Menoral may be taken with or without food, but it is better to take it at a fixed time.
How Menoral works
Menoral is a synthetic progestin. It works by mimicking the effects of natural progesterone (female hormone). It helps in regulating the growth and shedding of the womb lining, thereby treating menstrual irregularities.
Quick Tips
- Menoral regulates menstrual cycles and treats a wide range of menstrual disorders such as heavy, painful periods and endometriosis.
- It may cause bleeding or spotting in between menstrual periods. Let your doctor know if this occurs frequently.
- Stop taking Menoral and inform your doctor immediately if you get severe headaches, stabbing pains or swelling in one leg, pain while breathing, yellowing of your skin or sudden changes in your vision or hearing.
- Do not take Menoral if you are pregnant. Use a non-hormonal method of contraception such as condoms to prevent pregnancy while you are taking this medication, as it is not a contraceptive.
Brief Description
Indication
Breast cancer, Metropathia haemorrhagica (dysfunctional uterine bleeding), Premenstrual syndrome, Contraception, Endometriosis, Menorrhagia, Menopausal HRT
Administration
May be taken with or without food.
Adult Dose
Oral Adult Abnormal bleeding – 1 tablet three times a day for 10 days. Bleeding usually stops within 1-3 days. A period usually starts 2-4 days after stopping treatment. Prevention of abnormal bleeding – 1 tablet twice a day from the 19th - 26th day of the cycle. Premenstrual Syndrome - 2 to 3 tablets a day from the 19th - 26th day of the cycle. You will normally be treated for several months. Delaying a period - 1 tablet three times a day starting three days before the expected beginning of the period. Your period should occur 2-3 days...
... Show moreContraindication
Severe hepatic dysfunction; undiagnosed vaginal bleeding; porphyria; pregnancy; previous idiopathic or current thromboembolism; thromboembolic disease; DVT.
Mode of Action
Norethisterone has typical effects of a progestogen and converts the endometrium from the proliferative to the secretory phase. It may also have some oestrogenic, anabolic and androgenic activities, but these may not be significant. Norethisterone delays onset of periods and controls abnormal uterine bleeding. It also has contraceptive effects due to negative feedback inhibition of pituitary gonadotropin thus preventing ovulation.
Precaution
Hypertension; CVS disease; hepatic impairment; epilepsy; lactation; new onset of migraine-type headache; asthma; renal impairment; history of clinical depression.
Side Effect
Mental depression, cholestatic jaundice, porphyria, epilepsy, migraine, headache, breast discomfort, dizziness, nausea and vomiting, changes in libido, appetite and weight, breakthrough bleeding, changes in menstrual flow, amenorrhoea, oedema, rash, melasma or cholasma, acne, urticaria, abnormal LFTs, moodswings, insomnia, thrombotic and thromoembolic events, optic neuritis, altered lipid profile.
Interaction
Concentration may be reduced by CYP450 inducers (e.g. phenobarbital, phenytoin, carbamazepine, rifampicin, rifabutin, nevirapine, efavirenz, tetracyclines, ampicillin, oxacillin, co-trimoxazole) and ritonavir, nelfinavir (usually inhibitors of CYP450 but have inducing properties when used with steroid hormones). May cause additive fluid retention with NSAIDs, vasodilators. Adjustment in antidiabetic, thyroid hormone and anticoagulant therapy may be required.
Potentially Fatal: May increase ciclosporin concentration.
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