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Monotrate
Sun Pharmaceutical (Bangladesh) Ltd.
Generic: Isosorbide Mononitrate
Safety Advices
বাংলা
English
UNSAFE
Consuming alcohol while taking Monotrate may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
CONSULT YOUR DOCTOR
Monotrate may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
SAFE IF PRESCRIBED
Monotrate is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
UNSAFE
Monotrate may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
SAFE IF PRESCRIBED
Monotrate is safe to use in patients with kidney disease. No dose adjustment of Monotrate is recommended.
However, talk to your doctor if you have any underlying kidney disease.
SAFE IF PRESCRIBED
Monotrate is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Monotrate may not be needed in these patients. Please consult your doctor.
Medicine Overview of Monotrate 50mg Tablet
Introduction
Monotrate is used to prevent heart-related chest pain (angina). It works by relaxing and widening blood vessels so blood can flow more easily to the heart. This medicine will not treat an angina attack that has already begun. Monotrate should be taken empty stomach. Your doctor will decide the dose and how often you should take them. This may change from time to time depending on how well they are working. You should take this medicine as it has been prescribed and keep taking it, even if you feel well. This medicine helps to prevent chest pain in the future....
... Show moreUses of Monotrate
- Angina (heart-related chest pain)
Side effects of Monotrate
Common
- Headache
- Dizziness
- Increased heart rate
- Flushing (sense of warmth in the face, ears, neck and trunk)
- Orthostatic hypotension (sudden lowering of blood pressure on standing)
How to use Monotrate
Use it as advised by your doctor or check the label for directions before use. Monotrate is to be taken empty stomach.
How Monotrate works
Monotrate is a nitrate. It reduces the workload of the heart. As a result, the heart muscle does not need as much blood and oxygen supply.
What if you forget to take Monotrate?
If you miss a dose of Monotrate, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
- You have been prescribed Imdur 30mg Tablet PR for the prevention and treatment of heart-related chest pain (angina).
- Eat healthy (low-fat, high-fiber, low-sodium diet), quit smoking, increase your physical activity, watch your weight and reduce stress.
- Imdur 30mg Tablet PR may cause dizziness or sleepiness. Do not drive or do anything that requires concentration until you know how it affects you.
- Do not consume alcohol while taking Imdur 30mg Tablet PR as it may cause increased dizziness.
- It may cause headaches which usually go away after a few days of continued treatment. Inform your doctor if it persists.
- You may develop tolerance to Imdur 30mg Tablet PR with time, meaning that the same dose may be less effective next time. Follow the prescribed dosing schedule to avoid this.
- Stop taking medications (prescribed for erectile dysfunction) like sildenafil or tadalafil while on treatment with Imdur 30mg Tablet PR as it may cause low blood pressure.
Brief Description
Indication
Angina pectoris
Administration
Should be taken on an empty stomach (i.e. At least one hour before food or two hours after food).
Adult Dose
Oral
Angina Pectoris
Prevention of angina pectoris caused by coronary artery disease
Adult: 20 mg 2-3 times daily. Dose may range from 20-120 mg daily.
As LA form: One capsule once daily.
Elderly: Intiate at lower doses.
Child Dose
Safety and efficacy not established
Contraindication
Severe hypotension or anaemia, hypovolaemia, heart failure due to obstruction, or raised intracranial pressure due to head trauma or cerebral haemorrhage.
Mode of Action
Isosorbide mononitrate relaxes vascular smooth muscles by stimulating cyclic-GMP. It decreases left ventricular pressure (preload) and arterial resistance (afterload).
Precaution
Severe renal or severe hepatic impairment, hypothyroidism, malnutrition, or hypothermia. Caution in patients who are already hypotensive. May aggravate angina caused by hypertrophic cardiomyopathy. Tolerance may develop after long-term treatment. Lactation.
Lactation: Unknown whether drug crosses into breast milk; use caution
Side Effect
Hypotension, tachycardia, flushing, headache, dizziness, palpitation, syncope, confusion. Nausea, vomiting, abdominal pain. Restlessness, weakness and vertigo. Dry mouth, chest pain, back pain, oedema, fatigue, abdominal pain, constipation, diarrhoea, dyspepsia and flatulence.
Potentially Fatal: Severe hypotension and cardiac failure.
Interaction
Hypotensive effects may be increased when used with alcohol or vasodilators. Concurrent use with calcium channel blockers may lead to marked orthostatic hypotension.
Potentially Fatal: Significant hypotension may occur when used with phosphodiesterase-5 inhibitors.
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