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Myleran

Tablet-(2mg)
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Rainbow Traders

Generic: Busulphan

1 Tablet
৳ 9.36
৳ 10.30
9% OFF

Medicine Overview of Myleran 2mg Tablet

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Introduction

Myleran is used in the treatment of some cancers of blood like chronic myeloid leukaemia. It is used in combination with other cancer medicines during hematopoietic progenitor cell transplantation (HPCT). It may also be used to treat some other types of cancer. Myleran can be taken with or without food, but better to take it at the same time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. The most common side effects of this medicine include decreased blood cells (red cells, white cells, and platelets), nausea, vomiting, and loss of appetite. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Inform your doctor if you have a medical history, of bleeding disorders, heart or liver disease, radiation treatment or any infection. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. Inform your doctor immediately if you notice unusual bruising or bleeding or if you have dark, tarry, or bloody stools and sore throat. This medicine is known to reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with kidney, liver and heart function during treatment with this medicine. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Myleran

  • Blood cancer (Chronic myeloid leukaemia)

Side effects of Myleran

Common
  • Decreased blood cells (red cells, white cells, and platelets)
  • Abdominal pain
  • Anxiety
  • Nausea
  • Vomiting
  • Loss of appetite
  • Decreased magnesium level in blood
  • Decreased potassium level in blood
  • Diarrhea
  • Fever
  • Headache
  • Increased glucose level in blood
  • Insomnia (difficulty in sleeping)
  • Stomatitis (Inflammation of the mouth)

How to use Myleran

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Myleran may be taken with or without food, but it is better to take it at a fixed time.

How Myleran works

Myleran is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication.

What if you forget to take Myleran?

If you miss a dose of Myleran, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Quick Tips

  • Seek immediate medical attention if you have unusual bruising or bleeding, or signs of infection (fever, chills, body aches) as busulfan can lower the ability of your blood to clot and body to fight infections.
  • Inform your doctor if you have thalassemia (abnormal hemoglobin in blood), gout (arthritis due to impaired metabolism of uric acid) or if you have had radiotherapy.
  • Do not receive live vaccine while using busulfan, and avoid contact with individuals who have recently received the same.
  • Tell your doctor if you are or planning to become pregnant or are breastfeeding.
  • Common Side Effects.

Brief Description

Indication

Chronic myeloid leukaemia, Bone marrow transplantation, Polycythemia vera, Essential thrombocythemia,

Administration

May be taken with or without food. Take w/ chilled liqd, ensure adequate fluid intake.

Adult Dose

Oral Palliative treatment of chronic myeloid leukemia Adult: 60 mcg/kg daily. Maintenance: 0.5-2 mg daily. Max: 4 mg daily. Polycythemia vera Adult: 4-6 mg daily continued for 4-6 wk with blood counts monitoring. Essential thrombocythemia Adult: 2-4 mg daily. Conditioning regimens for bone marrow transplantation Adult: 3.5-4 mg/kg daily in divided doses for 4 days up to a total dose of 14-16 mg/kg. Usually used with cyclophosphamide for ablation of recipient's bone marrow.

Contraindication

Pregnancy and lactation. Hypersensitivity.

Mode of Action

Busulfan reacts with N-7 position of guanosine and interferes with DNA replication and RNA transcription by alkylating and cross-linking the DNA strands.

Precaution

Prior treatment with other myelosuppressive drugs, patients predisposed to seizures. May cause secondary malignancies (tumors, acute leukaemias, ovarian failure). Previous irradiation/therapy. Monitor blood counts carefully during therapy. Discontinue if lung toxicity develops.

Side Effect

GI symptoms, anorexia, wt loss, weakness, hyperpigmentation, amenorrhoea, cataracts, cough or hoarseness, impaired fertility and gonadal function, dry skin, liver damage, gynaecomastia. Potentially Fatal: Bone marrow depression manifesting as thrombocytopaenia, leucopaenia, anaemia. Interstitial pulmonary fibrosis (known as "busulfan lung" on prolonged treatment).

Interaction

Decreased clearance when used with cyclophosphamide and itraconazole. Increased clearance by phenytoin. May reduce response to vaccines, possibility of generalized infections with live vaccines. Combination with thioguanine results in oesophageal varices and abdominal liver function tests. Potentially Fatal: Cytotoxic agents may increase risk of pulmonary toxicity.

Buy Myleran from Arogga

In Bangladesh, you can get the original Myleran. Select your favorite one from a large collection of medicine products. Order from App to get more offers and better experience.

What is the price of Myleran in Bangladesh?

The latest price of Myleran in Bangladesh is 9.36৳. You can buy Myleran at the best price from Arogga. Order online through our website or mobile app and get fast home delivery anywhere in Bangladesh. Cash on Delivery (COD) is available all over Bangladesh.

Frequently Questions & Answers

Is the product authentic?

Yes. Arogga sources all medicines and health products directly from trusted suppliers, distributors, or manufacturers. Every product is verified before delivery.

Does Arogga deliver all over Bangladesh?

Yes, Arogga delivers nationwide. You can order from anywhere in Bangladesh.

Is Cash on Delivery(COD) available?

Yes, Cash on Delivery is available across Bangladesh for most products.

How long does delivery take?

Delivery usually takes 24–48 hours inside Dhaka and 3–5 days outside Dhaka, depending on location and courier load.

Can I return or replace the product?

If the product is damaged, incorrect, or expired, you can request a replacement or refund according to Arogga’s return policy.

Safety Advices

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CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Myleran. Please consult your doctor.
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CONSULT YOUR DOCTOR
Myleran is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
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UNSAFE
Myleran is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
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CONSULT YOUR DOCTOR
It is not known whether Myleran alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
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SAFE IF PRESCRIBED
Myleran is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Myleran may not be needed in these patients. Please consult your doctor.
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CONSULT YOUR DOCTOR
There is limited information available on the use of Myleran in patients with liver disease. Please consult your doctor.

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Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.