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Safety Advices
বাংলা
English
UNSAFE
It is unsafe to consume alcohol with Nicoral.
CONSULT YOUR DOCTOR
Nicoral may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
CONSULT YOUR DOCTOR
Information regarding the use of Nicoral during breastfeeding is not available. Please consult your doctor.
UNSAFE
Nicoral may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
SAFE IF PRESCRIBED
Nicoral is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Nicoral may not be needed in these patients. Please consult your doctor.
SAFE IF PRESCRIBED
Nicoral is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Nicoral may not be needed in these patients. Please consult your doctor.
Medicine Overview of Nicoral 5mg Tablet
Introduction
Nicoral is a medicine used to prevent and treat heart-related chest pain (angina). It is usually prescribed when other heart medicines are not suitable or have not worked. It reduces the risk of an angina attack by widening blood vessels and improving blood flow to the heart. Nicoral may be taken with or without food. It should be swallowed whole with water at the same time(s) each day. Your doctor will decide the dose and how often you should take it. This may change from time to time depending on how well it is working. You should take this medicine...
... Show moreUses of Nicoral
- Angina (heart-related chest pain)
Side effects of Nicoral
Common
- Headache
- Nausea
- Vomiting
- Weakness
- Dizziness
- Flushing (sense of warmth in the face, ears, neck and trunk)
How to use Nicoral
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nicoral may be taken with or without food, but it is better to take it at a fixed time.
How Nicoral works
Nicoral is a vasodilator. It works by reducing the workload of the heart. As a result, heart muscle does not need as much blood and oxygen supply. This reduces the frequency and severity of angina attacks.
What if you forget to take Nicoral?
If you miss a dose of Nicoral, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
- You must continue to take it as advised, usually for a long time.
- Nicoral may cause headaches. Drink plenty of water and take a suitable painkiller. Inform your doctor if it does not go away.
- Nicoral may cause dizziness or sleepiness. Do not drive or do anything which requires concentration until you know how it affects you.
- Do not consume alcohol while taking Nicoral as that may cause increased dizziness.
- Do not take medications like sildenafil or tadalafil (prescribed for erectile dysfunction) while on treatment with Nicoral as it may cause low blood pressure.
- Inform your doctor if you notice any bleeding from the anal passage, blood in vomit or black stools.
Brief Description
Indication
Angina pectoris
Administration
May be taken with or without food.
Adult Dose
Oral
Angina pectoris
Adult: 10 mg bid, increase if necessary. Usual dose: 10-20 mg bid. May use 5 mg bid for patients prone to headache. Max dose: 30 mg bid.
Hepatic impairment: Dose reduction may be necessary.
Contraindication
Cardiogenic shock; hypotension; left ventricular failure with low filling pressure; lactation.
Mode of Action
Nicorandil dilates arterioles and large coronary arteries by opening the potassium channels, and stimulates guanylate cyclase causing venous vasodilatation. It therefore reduces preload and afterload, and improves coronary blood flow.
Precaution
Hypovolaemia, low systolic BP, acute pulmonary oedema, pregnancy. May impair ability to drive or operate machinery.
Side Effect
Headache (usually transitory), flushing, dizziness, nausea, vomiting and weakness. Hypotension and reflex tachycardia at high doses.
Interaction
Hypotensive interaction may occur with alcohol, TCAs, antihypertensives and other vasodilators.
Potentially Fatal: Enhanced hypotensive effect with sildenafil and other phosphodiesterase type-5 inhibitors.
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