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Nitrest

Tablet-(10mg)
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Sun Pharmaceutical (Bangladesh) Ltd.

Generic: Zolpidem Tartrate

1 Tablet
৳ 4.70
৳ 5
6% OFF

Medicine Overview of Nitrest 10mg Tablet

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Introduction

Nitrest is a prescription medicine used for short term treatment of insomnia. It reduces sleep onset time and frequent awakening at night. This medicine improves sleep maintenance and therefore ensures sound sleep. Nitrest should be taken on an empty stomach, preferably just before going to bed. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor as it is habit forming. Do not stop taking it suddenly without talking to your doctor as it may worsen your symptoms. Some common side effects of this medicine include memory loss, hallucinations, agitation, headache, vertigo, diarrhea, nausea, vomiting and back pain. It may also cause fatigue, stomach pain, infections in the nose and throat, double vision and depression. However, these are temporary and resolve on their own after some time. Please consult your doctor if these bother you or do not away. Nitrest also causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you and do not take alcohol with it as it may worsen the dizziness. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, hallucinations or suicidal thoughts while taking this medicine. Before taking Nitrest, inform your doctor about all other medicines that you are taking, so that your doctor can advise if taking this medicine is right for you. Consult your doctor before taking this medicine if you are suffering from any liver or kidney problems. You should avoid smoking and alcohol while using this medicine. Pregnant and breastfeeding mothers should not use this medicine. However, if the need arises, please consult your doctor before using it.

Uses of Nitrest

  • Insomnia

Side effects of Nitrest

Common
  • Memory loss
  • Vertigo
  • Vomiting
  • Back pain

How to use Nitrest

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nitrest is to be taken empty stomach.

How Nitrest works

Nitrest belongs to a group of medicines called non-benzodiazepine hypnotics. It has hypnotic, sedative, and anticonvulsant (manages fits) properties. It works by binding of the GABAA receptor chloride channel macromolecular complex (a chemical messenger) that slows the activity of the nerve cells in the brain and helps fall asleep.

What if you forget to take Nitrest?

If you miss a dose of Nitrest, skip it and continue with your normal schedule. Do not double the dose.

Quick Tips

  • Your doctor has prescribed Nitrest to help you fall asleep faster and sleep for longer.
  • It is best taken without food as a high-fat meal can reduce its absorption and effect.
  • Take it 30 to 45 minutes before bedtime and only when you have time to sleep for at least 7 hours.
  • It makes you feel dizzy next morning. Don't drive or do anything requiring concentration until you know how it affects you.
  • It does not affect total sleep time. However, it reduces sleep onset time and frequent awakening at night.
  • Never share your medication with any other person who also has a sleep problem.
  • Inform your doctor if your sleep doesn’t improve after 7 to 10 days of treatment.
  • Stop taking medication and inform your doctor If you experience sleep driving or memory loss.
  • Do not stop taking medication suddenly as it may lead to anxiety, mood changes, and restlessness.

Brief Description

Indication

Insomnia

Administration

Should be taken on an empty stomach. Do not take w/ or immediately after a meal.

Adult Dose

Oral Short-term management of insomnia Adult: As immediate release tab: 5-10 mg immediately before bedtime. Max: 10 mg/day. Max duration of treatment: 4 wk including tapering. Elderly: As immediate release tab: 5 mg immediately before bedtime. Max duration of treatment: 4 wk including tapering. Hepatic impairment: As immediate release tab: 5 mg immediately before bedtime. Max duration of treatment: 4 wk including tapering. Severe: Contraindicated.

Child Dose

Not recommended

Renal Dose

Renal impairment: No dosage adjustment needed.

Contraindication

Severe hepatic impairment.

Mode of Action

Zolpidem is an imidazopyridine derivative that acts by binding to the benzodiazepine (BZD) receptors of the GABA receptor complex resulting in neuronal hyperpolarisation, action potential inhibition, increased in chloride conductance and decreased in neuronal excitability. It has strong sedative action but only minimal anxiolytic, myorelaxant and anticonvulsant properties due to its selectivity for the BZ1-receptor over the BZ2-receptor. Zolpidem has a rapid onset but short duration of hypnotic action.

Precaution

Obstructive sleep apnoea, myasthenia gravis, compromised respiratory function. Patients exhibiting symptoms of depression. History of drug or alcohol abuse. Avoid abrupt withdrawal and rapid dose reduction after prolonged therapy. Re-evaluate if insomnia fail to remit after 7-10 days as this may indicate the presence of underlying psychiatric and/or medical condition. Pregnancy, lactation, childn <18 yr. Patient Counseling Patients should be warned about performing activities involving mental alertness or physical coordination after drug intake. Lactation: Very low amounts secreted in breast milk; effect on infant unknown; use caution; advise mother to observe breastfeeding infant for lethargy, increased sedation, and changes in feeding habits

Side Effect

>10% Dizziness (5-12%),Headache (7-19%),Drowsiness (6-15%) 1-10% Allergy (4%),Hallucinations (4%),Myalgia (4%),Sinusitis (4%),Memory disorder (3%),Visual disturbance (3%),Pharyngitis (3%),Lightheadedness (2%),Palpitation (2%),Rash (2%),Constipation (2%),Depression (2%),Drowsiness (2%),Asthenia (1%),Diarrhea (1%),Dry mouth (1%),Flu-like symptoms (1%) Potentially Fatal: Hepatitis, anaphylactic reactions, angioedema, sleep-driving (driving while not fully awake after drug intake, w/ no recollection of the event).

Interaction

Flumazenil reverses the sedative/hypnotic effect of zolpidem. Increased depressant effects w/ CNS depressants (e.g. sedatives, antihistamines, alcohol). Additive effect on decreased alertness and psychomotor performance w/ imipramine and chlorpromazine. Increased plasma concentration w/ itraconazole, ketoconazole and other CYP3A4 inhibitors. May decrease plasma concentration w/ CYP3A4 inducers (e.g. carbamazepine). Reduced hypnotic effect w/ rifampicin. Potentially Fatal: Increased risk of prolonged sedation and respiratory depression w/ ritonavir.

Buy Nitrest from Arogga

In Bangladesh, you can get the original Nitrest. Select your favorite one from a large collection of medicine products. Order from App to get more offers and better experience.

What is the price of Nitrest in Bangladesh?

The latest price of Nitrest in Bangladesh is 4.7৳. You can buy Nitrest at the best price from Arogga. Order online through our website or mobile app and get fast home delivery anywhere in Bangladesh. Cash on Delivery (COD) is available all over Bangladesh.

Frequently Questions & Answers

Is the product authentic?

Yes. Arogga sources all medicines and health products directly from trusted suppliers, distributors, or manufacturers. Every product is verified before delivery.

Does Arogga deliver all over Bangladesh?

Yes, Arogga delivers nationwide. You can order from anywhere in Bangladesh.

Is Cash on Delivery(COD) available?

Yes, Cash on Delivery is available across Bangladesh for most products.

How long does delivery take?

Delivery usually takes 24–48 hours inside Dhaka and 3–5 days outside Dhaka, depending on location and courier load.

Can I return or replace the product?

If the product is damaged, incorrect, or expired, you can request a replacement or refund according to Arogga’s return policy.

Safety Advices

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UNSAFE
Nitrest may cause excessive drowsiness with alcohol.
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CONSULT YOUR DOCTOR
Nitrest may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
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SAFE IF PRESCRIBED
Nitrest is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
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UNSAFE
Nitrest may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
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SAFE IF PRESCRIBED
Nitrest is safe to use in patients with kidney disease. No dose adjustment of Nitrest is recommended. However, inform your doctor if you have any kidney disease.
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CAUTION
Nitrest should be used with caution in patients with liver disease. Dose adjustment of Nitrest may be needed. Please consult your doctor. Nitrest is generally started at a low dose in patients with mild to moderate liver disease and is not recommended in patients with severe liver disease.

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Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.