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Safety Advices
বাংলা
English
UNSAFE
Nomigran may cause excessive drowsiness with alcohol.
CONSULT YOUR DOCTOR
Nomigran may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
SAFE IF PRESCRIBED
Nomigran is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
UNSAFE
Nomigran may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
CONSULT YOUR DOCTOR
There is limited information available on the use of Nomigran in patients with kidney disease. Please consult your doctor.
CAUTION
Nomigran should be used with caution in patients with liver disease. Dose adjustment of Nomigran may be needed. Please consult your doctor.
Use of Nomigran is not recommended in patients with severe liver disease.
Medicine Overview of Nomigran 50mg Tablet
Introduction
Nomigran is a prescription medicine used in the treatment of migraine. It relieves the symptoms of migraine and prevents the attack from becoming worse. This medicine helps by narrowing the blood vessels, thereby relieving migraine headaches. Nomigran may be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Do not skip any doses and finish the full course of treatment even if you feel better and if you have missed a dose, take it as soon as you...
... Show moreUses of Nomigran
- Migraine
Side effects of Nomigran
Common
- Dizziness
- Weakness
- Flushing (sense of warmth in the face, ears, neck and trunk)
- Drowsiness
- Peripheral neuropathy (tingling and numbness of feet and hand)
How to use Nomigran
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nomigran may be taken with or without food, but it is better to take it at a fixed time.
How Nomigran works
Migraine headaches are thought to result from the dilatation (swelling) of blood vessels in the head. Nomigran works by constricting (narrowing) the blood vessels in the head, stops transmission of pain signals to the brain, and blocks the release of chemicals that cause nausea and other migraine symptoms. This relieves the migraine attack.
Quick Tips
- You have been prescribed Nomigran for treatment of migraine headaches.
- Some tips that may help avoid a migraine attack:
- It may cause sleepiness. Don't drive or do anything that requires mental focus until you know how it affects you.
- Notify your doctor if your migraine occurs more often after starting the medication.
- Notify your doctor if you have stomach pain, headache, bloody diarrhoea or worsening high blood pressure.
- Inform your doctor if you have a history of heart disease or stroke.
- This medication does not prevent migraine attacks from happening.
Brief Description
Indication
Migraine, Cluster headache
Administration
May be taken with or without food.
Adult Dose
Oral
Migraine
Adult: >18 yr: 50-100 mg repeated at 2-hr intervals if migraine recurs. Max: 200 mg/24 hr.
Mild to moderate hepatic impairment: Max single dose: 50 mg.
Severe hepatic impairment: Contraindicated
Child Dose
<18 years: Safety and efficacy not established
Contraindication
Not to be used prophylactically and in patients with basilar or hemiplegic or ophthalmoplegic migraine. History of MI or stroke, severe hepatic impairment, ischaemic heart disease, uncontrolled hypertension, peripheral vascular disease, hypersensitivity to sulfonamides.
Mode of Action
Sumatriptan is a selective serotonin agonist that acts at 5-HT1 receptors. It causes vasoconstriction of cranial arteries and/or inhibition of neurogenic inflammatory processes in the CNS. A small but significant delay in gastric emptying also occurs.
Precaution
Conditions predisposing to seizures, presence of coronary risk factors, cardiac arrhythmias, renal or hepatic impairment, elderly, pregnancy, lactation.
Lactation: Excreted in breast milk at very low levels; minimize infant to potential exposure by avoiding breastfeeding for 8-12 hours after administration
Side Effect
>10%
Injection site reaction (<86%),Paresthesia (5-14%),Dizziness (12%),Warm/hot sensation (11%)
1-10%
Chest discomfort/pressure/tightness (2-5%),Jaw or neck tightness (1-5%),Diaphoresis (2%),Burning sensation (7%),Cold sensation (1%),Dysphagia,Sore throat (3%),Malaise (1%),Abdominal distress (1%)
Frequency Not Defined
Agitation,Cardiac arrhythmia: V-fib/V-tach (rare),Dysuria,Eye irritation,Flushing,MI and coronary artery vasospasm in patients with CAD risk factors (extremely rare),Nasal discomfort,Palpitations,Tingling,Weakness
Potentially Fatal: Cardiac arrhythmias, MI.
Interaction
Concurrent use increased risk of vasospastic reaction with ergotamine and related compounds.
Potentially Fatal: Increased risk of serotonin syndrome with concurrent use of SSRI, MAOIs or within 14 days of stopping MAOIs. Admin of ergotamine or related compounds within the previous 24 hr.
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