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NPV

Tablet-(10mg+10mg)
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Ziska Pharmaceuticals Ltd.

Generic: Doxylamine + Pyridoxine

1 Tablet
৳ 4.55
৳ 5
9% OFF
Alternative Brands For NPV

Medicine Overview of NPV 10mg+10mg Tablet

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Introduction

NPV is a combination medicine used to treat nausea and vomiting during pregnancy. It prevents the feeling of nausea and sickness in pregnant women. It also provides nutrition to the body. NPV is a prescription medicine. It is advised to take it as per the prescription. It can be taken with or without food, but it must be taken at a fixed time to ensure better efficacy. Do not consume more than the recommended dose, as this may have harmful effects on your body. If you miss a dose, take it as soon as you remember. The course of the treatment must be completed even if you feel better. Sudden discontinuation of the treatment may affect the potency of the medicine. Some common side effects of this medicine are dizziness, stomach pain, constipation, etc. To cope up with the side effects, you should drink plenty of fluid. If any of the side effects get aggravated, contact your doctor immediately. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must seek immediate medical help. Before taking this medicine, you should tell your doctor if you are taking any medicine for any health condition. Avoid drinking alcohol as it can cause excessive dizziness, also can harm the baby in the womb. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy. You must take adequate rest for a faster recovery, also take a healthy diet. To avoid nausea and vomiting during pregnancy, you may drink lemon-infused water. You can also add salad sprinkled with black salt to your diet. Visit your doctor regularly for laboratory and diagnostic tests as per advice.

Uses of NPV

  • Nausea and vomiting in pregnancy

Side effects of NPV

Common
  • Dryness in mouth
  • Constipation
  • Lightheadedness
  • Drowsiness

How to use NPV

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. NPV may be taken with or without food, but it is better to take it at a fixed time.

How NPV works

NPV is a combination of two medicines: Doxylamine and vitamin B6 (pyridoxine), which treats nausea and vomiting associated with pregnancy. Doxylamine is an antihistamine which works by blocking the action of a chemical messenger (histamine), thereby controlling nausea, vomiting, and dizziness. Pyridoxine (vitamin B6) is a form of vitamin B which possesses anti-nausea properties.

Quick Tips

  • NPV helps treat nausea and vomiting in pregnant women.
  • Take it on an empty stomach with a glass of water.
  • NPV may cause dizziness. Do not drive or do anything requiring concentration until you know how it affects you.
  • Do not take NPV with other sedating medications such as those for cough and cold as the combination could worsen dizziness leading to falls or other accidents.
  • Do not take NPV while breastfeeding.

Brief Description

Indication

Nausea & Vomiting of Pregnancy

Administration

Take on empty stomach with water; food further delays onset of action and lowers peak levels Swallow tablet whole, do not chew, crush, or split

Adult Dose

Oral Nausea & Vomiting of Pregnancy Indicated for the treatment of nausea and vomiting of pregnancy in women who do not respond to conservative management Delayed-release Tablet 2 delayed-release tablets PO on a daily basis at bedtime If symptoms not adequately controlled, increase dose to 4 tablets each day (1 tab in AM, 1 tab mid-afternoon, and 2 tabs at bedtime) Conventional Tablet Initially, take one tablet orally at bedtime (Day 1). If this dose adequately controls symptoms the next day, continue taking one tablet daily at bedtime only. If symptoms persist, increase the daily dose to one tablet in the morning and one tablet at bedtime. The maximum recommended dose is two tablets per day, one in the morning and one at bedtime.

Child Dose

<18 years: Safety and efficacy not established

Contraindication

Hypersensitivity MAO inhibitors intensify and prolong doxylamine’s adverse effects (ie, anticholinergic, CNS)

Mode of Action

Doxylamine: Ethanolamine derivative antihistamine Pyridoxine: Vitamin B6 analog Doxylamine is an antihistamine that blocks Histamine (H1) receptor. It affects the vestibular system and decreases the stimulation of the vomiting center. Its mascarinic receptor inhibition may also play a role in antihistamine antiemetic activity. Pyridoxine (Vitamin B6) is a vitamin used to prevent nausea and vomiting due to its antiemetic properties.

Precaution

Coadministration with alcohol and other CNS depressants may cause additive sedation and is not recommended; combination may cause severe drowsiness leading to falls or accidents Somnolence due to anticholinergic effects is common; avoid activities requiring mental alertness Anticholinergic effects may exacerbate conditions such as asthma, increased intraocular pressure, narrow angle glaucoma, stenosing peptic ulcer, pyloroduodenal obstruction, and urinary bladder-neck obstruction Lactation: Do not breast feed; doxylamine molecular weight is low enough to distribute into human breast milk Excitement, irritability, and sedation reported in nursing infants presumably exposed to doxylamine through breast milk; infants with apnea or other respiratory syndromes may be particularly vulnerable to the sedative effects resulting in worsening of apnea or respiratory conditions Pyridoxine is excreted in breast milk; there have been no reports of adverse effects in infants

Side Effect

>10% Somnolence (14.3%)

Pregnancy Category Note

Pregnancy Intended for treatment of nausea and vomiting of pregnancy in women who do not respond to conservative management; maternal risks are discussed throughout the labeling; no increased risk for congenital malformations reported in epidemiologic studies in pregnant women Lactation Women should not breastfeed while on therapy; molecular weight of doxylamine succinate is low enough that passage into breast milk can be expected; excitement, irritability and sedation reported in nursing infants presumably exposed to doxylamine succinate through breast milk; infants with apnea or other respiratory syndromes may be particularly vulnerable to sedative effects of drug resulting in worsening of their apnea or respiratory conditions Pyridoxine hydrochloride is excreted into breast milk; adverse events in infants presumably exposed to pyridoxine hydrochloride through breast milk reported

Buy NPV from Arogga

In Bangladesh, you can get the original NPV. Select your favorite one from a large collection of medicine products. Order from App to get more offers and better experience.

What is the price of NPV in Bangladesh?

The latest price of NPV in Bangladesh is 4.55৳. You can buy NPV at the best price from Arogga. Order online through our website or mobile app and get fast home delivery anywhere in Bangladesh. Cash on Delivery (COD) is available all over Bangladesh.

Frequently Questions & Answers

Is the product authentic?

Yes. Arogga sources all medicines and health products directly from trusted suppliers, distributors, or manufacturers. Every product is verified before delivery.

Does Arogga deliver all over Bangladesh?

Yes, Arogga delivers nationwide. You can order from anywhere in Bangladesh.

Is Cash on Delivery(COD) available?

Yes, Cash on Delivery is available across Bangladesh for most products.

How long does delivery take?

Delivery usually takes 24–48 hours inside Dhaka and 3–5 days outside Dhaka, depending on location and courier load.

Can I return or replace the product?

If the product is damaged, incorrect, or expired, you can request a replacement or refund according to Arogga’s return policy.

Safety Advices

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CAUTION
Caution is advised when consuming alcohol with NPV. Please consult your doctor.
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SAFE IF PRESCRIBED
NPV is safe to use during pregnancy. Most studies have shown low or no risk to the developing baby.
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SAFE IF PRESCRIBED
NPV is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. Larger doses or prolonged use of NPV may cause sleepiness and other effects in the baby
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UNSAFE
NPV may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
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SAFE IF PRESCRIBED
NPV is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of NPV may not be needed in these patients. Please consult your doctor.
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SAFE IF PRESCRIBED
NPV is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of NPV may not be needed in these patients. Please consult your doctor.

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Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.