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Safety Advices
বাংলা
English
UNSAFE
Nubis may cause excessive drowsiness with alcohol.
CONSULT YOUR DOCTOR
Information regarding the use of Nubis during pregnancy is not available. Please consult your doctor.
CONSULT YOUR DOCTOR
Nubis is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
UNSAFE
Nubis may cause side effects which could affect your ability to drive.
CAUTION
Nubis should be used with caution in patients with kidney disease. Dose adjustment of Nubis may be needed. Please consult your doctor.
Regular blood pressure monitoring is advisable for dose adjustment.
CAUTION
Nubis should be used with caution in patients with liver disease. Dose adjustment of Nubis may be needed. Please consult your doctor.
Nubis is started at a lower dose in these patients and further increased slowly with careful monitoring.
Medicine Overview of Nubis 2.5mg Tablet
Introduction
Nubis belongs to a group of medicines called beta-blockers. It is used to treat high blood pressure (hypertension), angina (heart-related chest pain), irregular heart rhythms (arrhythmia). It also helps to prevent future heart attacks and stroke and to prevent migraine. Nubis is also used to relieve the symptoms caused by an overactive thyroid gland. It may be prescribed alone or together with other medications. The dose and frequency depend on what you are taking it for and the severity of your condition. It may be taken empty stomach or with a meal, but take it regularly at the same time...
... Show moreUses of Nubis
- Hypertension (high blood pressure)
- Angina (heart-related chest pain)
- Heart failure
Side effects of Nubis
Common
- Nausea
- Headache
- Fatigue
- Constipation
- Diarrhea
- Dizziness
- Cold extremities
How to use Nubis
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nubis may be taken with or without food, but it is better to take it at a fixed time.
How Nubis works
Nubis is a beta blocker that works specifically on the heart. It works by slowing down the heart rate and makes the heart more efficient at pumping blood around the body.
Quick Tips
- It may cause dizziness. If this happens to you, get up slowly when rising from a sitting or lying position.
- It can hide symptoms of low blood sugar if you are diabetic. Monitor your blood sugar levels regularly.
- Do not stop taking Nubis suddenly as it can cause your blood pressure to rise suddenly, thereby increasing the risk of heart attack and stroke.
Brief Description
Indication
Hypertension, Angina pectoris, Congestive heart failure
Administration
May be taken with or without food.
Adult Dose
The usual starting dose is 5 mg once daily. In some patients, 2.5 mg may be an appropriate starting dose. If the antihypertensive effect of 5 mg is inadequate, the dose may be increased to 10 mg and then, if necessary, to 20 mg once daily. For heart failure: Initially 1.25 mg once daily (in the morning) for 1 week then, if well tolerated, increased to 2.5 mg once daily for 1 week, then 3.75 mg once daily for 1 week, then 5 mg once daily for 4 weeks, then 7.5 mg once daily for 4 weeks, then 10 mg...
... Show moreRenal Dose
Renal impairment:
CrCl (ml/min)
<40 Initial: 2.5 mg/day.
Contraindication
Patients with cardiogenic shock, overt cardiac failure, second or third degree AV block and marked sinus bradycardia.
Mode of Action
Bisoprolol selectively and competitively blocks beta1-receptors but has little or no effect on beta2-receptors except at high doses.
Precaution
Impaired Renal or Hepatic Function.
Lactation: excretion in milk unknown; use caution
Side Effect
1-10%
Dizziness (10%),Dyssomnia (8%-10%),Bradyarrhythmia (9%),Upper respiratory infection (5%),Diarrhea (4%),Rhinitis (4%),Arthralgia (3%),Cough (3%),Dyspnea (2%),Nausea (2%),Pharyngitis (2%),Sinusitis (2%),Vomiting (2%)
<1%
Cold extremities,Hypotension,Depression,Dyspepsia,Bronchospasm
Frequency Not Defined
Aggravate CHF,Decrease HDL,Hypertriglyceridemia,Mask symptoms of hypoglycemia,Decreased exercise tolerance,Raynaud's phenomenon,May increase triglyceride levels and insulin resistance
Pregnancy Category Note
Pregnancy Category: C
Lactation: excretion in milk unknown; use caution
Interaction
May potentiate AV conduction time and may increase negative inotropic effect w/ class I antiarrhythmic drugs (e.g. quinidine, disopyramide, propafenone). Concomitant catecholamine-depleting drugs (e.g. reserpine, guanethidine) may produce excessive sympathetic activity. May exacerbate rebound HTN upon discontinuance of clonidine treatment. Increased risk of bradycardia w/ digitalis glycosides. Reduced hypotensive effect w/ NSAIDs.
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