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ব্যবসার জন্য পাইকারি দামে পণ্য কিনতে রেজিস্টেশন করুন

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Aphrin IV/IM

Name: Aphrin IV/IM 1gm/vial Injection
Brand: Apex Pharma Ltd.
SKU: 1349
Price: 72.99 BDT
Availability: InStock
Rating: 4.9 (1 reviews)

Injection - (1gm/vial)

Apex Pharma Ltd.

Generic: Cephradine

Medicine Overview of Aphrin IV/IM 1gm/vial Injection

বাংলা

English

Indication

Pneumonia, Pharyngitis, Susceptible infections, Otitis media, Skin and Skin-Structure Infections, Rheumatic fever, Tonsillitis, Respiratory tract infections, Urinary tract infections, Surgical Prophylaxis, Genitourinary tract infections, Acute prostatitis

Administration

May be taken with or without food. May be taken w/ meals to reduce GI discomfort. Parenteral doses by deep IM or slow IV inj over 3-5 min or by IV infusion. Reconstitution: IM: Add 2 mL or 4 mL of sterile water for inj or NaCl 0.9% inj to 500 mg or 1 g vial, respectively. IV: Add 5 mL of sterile water for inj, dextrose 5% inj, NaCl 0.9% inj or other suitable soln to 500 mg vial. Shake well the entire soln.

Adult Dose

Adult: PO Susceptible infections 1-2 g/day in 2-4 divided doses. Max: 4 g/day. Surgical prophylaxis 1-2 g pre-op. Subsequent doses may be given as needed. Skin and skin structures and respiratory tract infection: Usual dose is 250 mg every 6 hours or 500 mg every 12 hours. Lobar pneumonia: 500 mg every 6 hours or 1 gm every 12 hours. Urinary tract infection: Usual dose is 500 mg every 12 hours. Gastro-intestinal tract infection: 500 mg three to four times daily. IV/IM Severe infections 2-4 g/day in 4 divided doses. Max: 8 g/day.

Child Dose

Children: Oral: The usual total dose is 25 to 50 mg/kg/day given in 2 to 4 equally divided doses. Injection: 50 to 100 mg/kg/day in 4 equally divided doses. The usual total dose may be increased up to 200-300 mg/kg/day. Perioperative prophylaxis: Recommended dose is 1-2 gm by intramuscular or intravenous route; subsequent parenteral or oral doses are given as appropriate.

Renal Dose

Renal impairment: For patients undergoing chronic intermittent haemodialysis: 250 mg may be given at the start of the session, repeated after 6-12 hr, then again 36-48 hr after the initial dose, and again at the start of the next haemodialysis if >30 hr have elapsed since the previous dose. CrCl (ml/min) >20 500 mg every 6 hr. 5-20 250 mg every 6 hr. <5 250 mg every 12 hr.

Contraindication

Hypersensitivity to cefradine or other cephalosporins; porphyria.

Mode of Action

Cefradine is a 1st generation cephalosporin which inhibits the final transpeptidation step of the peptidoglycan synthesis in bacterial cell wall by binding to one or more of the penicillin-binding proteins (PBPs), thus arresting cell wall synthesis leading to bacterial cell death.

Precaution

Renal impairment; history of penicillin sensitivity; pregnancy; lactation.

Side Effect

Diarrhoea, nausea, vomiting; leukopenia, neutropenia, eosinophilia, rash, pruritus; joint pain; increased BUN and creatine; dizziness. Potentially Fatal: Pseudomembranous colitis.

Interaction

Increased risk of nephrotoxicity w/ loop diuretics. Decreased renal clearance w/ probenecid.

ব্যবসার জন্য পাইকারি দামে পণ্য কিনতে রেজিস্টেশন করুন

0 People recently viewed this

Aphrin IV/IM

Injection - (1gm/vial)

Apex Pharma Ltd.

Generic: Cephradine

Additional Offers

Cashback

৳50

For purchasing above ৳5000+

Cashback

৳40

For purchasing above ৳4000+

Cashback

৳30

For purchasing above ৳3000+

Cashback

৳20

For purchasing above ৳2000+

Cashback

৳10

For purchasing above ৳1000+

Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.

Aphrin IV/IM

Medicine Overview of Aphrin IV/IM 1gm/vial Injection

Aphrin IV/IM

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