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Orbuten
Aristopharma Limited
Generic: Ceftibuten
Safety Advices
বাংলা
English
SAFE
Consuming alcohol with Orbuten does not cause any harmful side effects.
SAFE IF PRESCRIBED
Orbuten is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
CAUTION
Orbuten should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
SAFE
Orbuten does not usually affect your ability to drive.
CAUTION
Orbuten should be used with caution in patients with kidney disease. Dose adjustment of Orbuten may be needed. Please consult your doctor.
CONSULT YOUR DOCTOR
There is limited information available on the use of Orbuten in patients with liver disease. Please consult your doctor.
Medicine Overview of Orbuten 90mg/5ml Powder for Suspension
Introduction
Orbuten is an antibiotic medicine used to treat bacterial infections in your body. It is effective in infections of the lungs (eg. pneumonia), urinary tract, ear, nasal sinus, and throat. It kills bacteria, which helps to improve your symptoms and cure the infection. Orbuten may be taken with or without food. You should take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time every day will help you to remember to take it. The dose will depend on what you are being treated for, but you should always complete...
... Show moreUses of Orbuten
- Bacterial infections
Side effects of Orbuten
Common
- Allergic reaction
- Stomach pain
- Diarrhea
How to use Orbuten
Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Orbuten may be taken with or without food, but it is better to take it at a fixed time.
How Orbuten works
Orbuten is an antibiotic. It kills the bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for them to survive.
What if you forget to take Orbuten?
If you miss a dose of Orbuten, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
- Your doctor has prescribed Orbuten to cure your infection and improve your symptoms.
- Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection harder to treat.
- Discontinue Orbuten and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.
- Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it does not stop or if you find blood in your stools.
- Take it with food to avoid an upset stomach.
- Avoid consuming alcohol while taking Orbuten as it may cause increased side effects.
Brief Description
Indication
Respiratory tract infections, Urinary tract infections
Administration
Susp: Should be taken on an empty stomach. Take 2 hr before or 1 hr after meals.
Cap: May be taken with or without food.
Adult Dose
Oral
Respiratory tract infections, Urinary tract infections
Adult: 400 mg once daily for 10 days.
Child Dose
Child:
12 years old or >45 kg: As in adults
Renal Dose
Renal impairment:
CrCl (ml/min)
30-49 200 mg once daily.
5-29 100 mg once daily.
Contraindication
Hypersensitivity to cephalosporins.
Mode of Action
Ceftibuten inhibits bacterial cell wall synthesis. It is stable to hydrolysis by many beta-lactamases and has greater activity than 1st or 2nd generation cephalosporins against gm-ve bacteria. It is less active in vitro than cefexime against S. pneumoniae.
Precaution
Hypersensitivity to penicillins; renal impairment; Porphyria. Monitor renal and haematologic status.
Lactation: excretion in milk unknown; use with caution
Side Effect
1-10%
Increased BUN (4%),Nausea (4%),Diarrhea (3%),Headache (3%),Increased eosinophils (3%),Decreased hemoglobin (2%),Dyspepsia (2%),Thrombocytosis (2%),Abdominal pain (1%),Dizziness (1%),Increased ALT (1%),Increased bilirubin (1%),Vomiting (1%)
<1%
Anorexia,Candidiasis,Constipation,Dysuria,Agitation,Fatigue,Insomnia,Irritability,Paresthesia,Rigors,Diaper rash,Urticaria,Dry mouth,Dyspnea,Nasal congestion,Increased transaminases,Increased creatinine,Leukopenia
Potentially Fatal: Pseudomembranous colitis.
Pregnancy Category Note
Pregnancy Category: B
Lactation: excretion in milk unknown; use with caution
Interaction
Enhanced nephrotoxicity of aminoglycosides. Increased serum concentration w/ probenecid. Decreased serum concentration w/ zinc salts.
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