12-24 Hours
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Safety Advices
বাংলা
English
UNSAFE
It is unsafe to consume alcohol with Aptin 50.
CONSULT YOUR DOCTOR
Aptin 50 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
CONSULT YOUR DOCTOR
Information regarding the use of Aptin 50 during breastfeeding is not available. Please consult your doctor.
UNSAFE
Aptin 50 may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
CAUTION
Aptin 50 should be used with caution in patients with kidney disease. Dose adjustment of Aptin 50 may be needed. Please consult your doctor.
CAUTION
Aptin 50 should be used with caution in patients with liver disease. Dose adjustment of Aptin 50 may be needed. Please consult your doctor.
Regular monitoring of liver function tests is recommended if you are taking this medicine. Use of $med_name is preferably not advised in patients with liver disease.
Medicine Overview of Aptin 50mg Tablet
Introduction
Aptin 50 is a medicine used to treat type 2 diabetes mellitus. It is used together with a healthy diet and regular exercise to control blood sugar levels. This helps to prevent serious complications of diabetes like kidney damage and blindness. Aptin 50 is normally prescribed when diet and exercise alone or other medicines do not prove sufficient to control your blood sugar level. Your doctor may prescribe it alone or along with other diabetes medicines. It can be taken with or without food. The dose will depend on your condition and blood sugar levels. Therefore, you should use it...
... Show moreUses of Aptin 50
- Type 2 diabetes mellitus
Side effects of Aptin 50
Common
- Headache
- Common cold
- Cough
- Constipation
- Dizziness
- Sweating
- Hypoglycaemia (low blood sugar level) in combination with insulin or sulphonylurea
How to use Aptin 50
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Aptin 50 may be taken with or without food, but it is better to take it at a fixed time.
How Aptin 50 works
Aptin 50 is an antidiabetic medication. It works by increasing the release of insulin from the pancreas and decreasing the hormones that raise blood sugar levels. This reduces the fasting and postmeal sugar levels.
What if you forget to take Aptin 50?
If you miss a dose of Aptin 50, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
- Aptin 50 should be taken at the same time every day since this helps you remember to take it.
- It may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
- Always carry some sugary food or fruit juice with you in case you experience hypoglycemia symptoms such as cold sweats, cool pale skin, tremor and anxiety.
- Be careful while driving or operating machinery until you know how Aptin 50 affects you.
- Your doctor may check your kidney and liver function before starting treatment and regularly thereafter. Inform your doctor if you develop symptoms such as abdominal pain, fatigue, loss of appetite, darkened urine or yellowing of the eyes or skin (jaundice).
Brief Description
Indication
Type 2 DM
Administration
May be taken with or without food.
Adult Dose
Oral
Type 2 diabetes mellitus
Adult: 50 mg bid. Not recommended to use >100 mg/day.
W/ metformin or a thiazolidinedione: 50 mg twice daily; w/ a sulfonylurea: 50 mg/day in the morning.
Renal Dose
Renal impairment: Moderate, severe and ESRD: 50 mg once daily.
Contraindication
Hypersensitivity to vildagliptin
Mode of Action
Vildagliptin is a dipeptidylpeptidase-4 (DPP-4) inhibitor that improves glycaemic control by preventing DPP-4 from inactivating the incretin hormones glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide, thus prolonging incretin activity in response to ingestion of nutrients. This increases insulin sensitivity, decreases glucagon secretion and improves ?-cell function.
Precaution
Patient w/ cardiac failure (NYHA functional class IV), type 1 DM; history of acute pancreatitis. Not intended for the treatment of diabetic ketoacidosis. Hepatic impairment, including patients w/ pre-treatment ALT or AST >3 times the upper limit of normal (ULN). Moderate or severe renal impairment, ESRD. Monitoring Parameters Monitor liver function.
Side Effect
Nausea, peripheral oedema, headache, tremor, asthenia, dizziness, constipation, hypoglycaemia, arthralgia, hepatic dysfunction, nasopharyngitis, upper resp tract infection, pancreatitis, exfoliative and bullous skin reactions.
Interaction
Decreased hypoglycaemic effect w/ thiazides, corticosteroids, thyroid products and sympathomimetics.
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