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Safety Advices
বাংলা
English
UNSAFE
It is unsafe to consume alcohol with Orpan.
CONSULT YOUR DOCTOR
Orpan may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
CONSULT YOUR DOCTOR
Orpan is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
UNSAFE
Orpan may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
SAFE IF PRESCRIBED
Orpan is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Orpan may not be needed in these patients. Please consult your doctor.
Regular monitoring of kidney function tests is advisable while you are taking this medicine.
CONSULT YOUR DOCTOR
There is limited information available on the use of Orpan in patients with liver disease. Please consult your doctor.
Medicine Overview of Orpan 300mg Capsule
Introduction
Orpan is a pain relieving medicine. It effectively alleviates pain and inflammation in conditions like rheumatoid arthritis, osteoarthritis and acute pain. Orpan should be taken in the dose and duration as advised by your doctor. It should be taken with food or milk to prevent stomach upset. Inform your doctor if you have any history of heart disease or stroke. Vomiting, stomach pain, nausea and indigestion are some of the common side effects that might be observed on taking this medicine. It may also cause dizziness, drowsiness or visual disturbances. Your doctor may regularly monitor your kidney function, liver function...
... Show moreUses of Orpan
- Pain relief
Side effects of Orpan
Common
- Vomiting
- Stomach pain/epigastric pain
- Nausea
- Indigestion
- Loss of appetite
- Diarrhea
- Heartburn
How to use Orpan
Use it as advised by your doctor or check the label for directions before use. Orpan is to be taken with food.
How Orpan works
Orpan is a non-steroidal anti-inflammatory drugs (NSAID). It works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling).
Quick Tips
- You have been prescribed Proxym ER Tablet to relieve pain and inflammation.
- Take it with food or milk to prevent upset stomach.
- Take it as per the dose and duration prescribed by your doctor. Long term use may lead to serious complications such as stomach bleeding and kidney problems.
- It may cause dizziness, drowsiness or visual disturbances. Use caution while driving or doing anything that requires concentration.
- Avoid consuming alcohol while taking Proxym ER Tablet as it can cause excessive drowsiness and increase your risk of stomach problems.
- Inform your doctor if you have a history of heart disease or stroke.
- Your doctor may regularly monitor your kidney function, liver function and levels of blood components, if you are taking this medicine for long-term treatment.
Brief Description
Indication
Rheumatoid arthritis, Pain, Osetoarthritis
Administration
Should be taken with food. Take w/ or immediately after meals.
Adult Dose
Oral
Osteoarthritis; Rheumatoid arthritis
Adult: 600-1000 mg/day in divided doses adjusted according to response. Max: 1200 mg/day.
ER tablet: Once daily
Hepatic impairment: Dose adjustment not necessary
Child Dose
Juvenile Rheumatoid Arthritis
60 kg (extended release): 1000 mg PO once daily
Renal Dose
Mild-to-moderate renal impairment: Dose adjustment not necessary
Severe renal impairment; Not recommended
Contraindication
Peptic ulcer, hypersensitivity to etodolac/NSAIDs. Childn; pregnancy (3rd trimester) and lactation.
Mode of Action
Etodolac is an NSAID derived from pyrano-indoleacetic acid, inhibits cyclooxygenase 2 (COX-2) resulting in decreased prostaglandin precursor formation.
Precaution
CHF, dehydration, impaired renal, hepatic function, history of GI disease. Elderly, patients receiving anticoagulant.
Lactation: Unknown whether drug is excreted in breast milk; not recommended
Side Effect
1-10%
Dyspepsia (10%),Dizziness (3-9%),Nervousness (1-3%),Pruritus (1-3%),Blurred vision (1-3%),Depression (1-3%),Chills/fever (1-3%)
>1%
Asthenia, malaise,Blurred vision,Bronchospasm,Dysuria, urinary frequency,Edema,Melena,Rash,Tinnitus
Potentially Fatal: Acute renal failure; blood disorder; nephrotoxicity; angioedema, arrhythmia, bone marrow suppression, CHF, dyspnoea, erythema multiforme, exfoliative dermatitis, hepatitis, hypertension, peripheral neuropathy, Stevens-Johnson syndrome, syncope, tachycardia, toxic amblyopia, toxic epidermal necrolysis, urticaria.
Pregnancy Category Note
Pregnancy category: C; avoid in late pregnancy (may cause premature closure of ductus arteriosus)
Lactation: Unknown whether drug is excreted in breast milk; not recommended
Interaction
Increased effect of warfarin, lithium, methotrexate, digoxin, cyclosporin, aspirin. Effect may be reduced with aspirin. Reduced effect of some diuretics and ?-blockers. Alcohol enhances gastric mucosal irritation.
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