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Oseflu 75
Beximco Pharmaceuticals Ltd.
Generic: Oseltamivir
Safety Advices
বাংলা
English
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Oseflu 75. Please consult your doctor.
CONSULT YOUR DOCTOR
Oseflu 75 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
SAFE IF PRESCRIBED
Oseflu 75 is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
SAFE
Oseflu 75 does not usually affect your ability to drive.
CAUTION
Oseflu 75 should be used with caution in patients with kidney disease. Dose adjustment of Oseflu 75 may be needed. Please consult your doctor.
CAUTION
Oseflu 75 should be used with caution in patients with severe liver disease. Dose adjustment of Oseflu 75 may be needed. Please consult your doctor.
Limited information is available on use of Oseflu 75 in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.
Medicine Overview of Oseflu 75mg Capsule
Introduction
Oseflu 75 is an antiviral medicine used to treat and prevent influenza (flu) as well as, swine flu (H1N1 virus). It helps to relieve the symptoms of the flu virus infection like a stuffy or runny nose, sore throat, cough, body aches, tiredness, headache, fever, and chills. Oseflu 75 prevents the flu virus from spreading inside the body. Influenza, commonly known as flu is an infection caused by a virus. This medicine should be taken only when prescribed by a doctor. It should be used in the dose and duration as advised by your doctor. It can be taken with...
... Show moreUses of Oseflu 75
- Influenza (flu)
Side effects of Oseflu 75
Common
- Nausea
- Vomiting
- Abdominal pain
- Diarrhea
How to use Oseflu 75
Take this medicine in the dose and duration as advised by your doctor. Do not chew, crush or break it. Oseflu 75 may be taken with or without food, but it is better to take it at a fixed time.
How Oseflu 75 works
Oseflu 75 is a neuraminidase inhibitor. It inhibits neuraminidase (influenza virus enzyme) that helps the viruses to enter into uninfected cells of the body to cause or spread influenza infection in the body. This is how it works against the virus to treat influenza (flu).
What if you forget to take Oseflu 75?
If you miss a dose of Oseflu 75, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
- Oseflu 75 helps in the treatment and prevention of flu.
- Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the symptoms of flu to come back.
- Take it as soon as possible, ideally within two days of starting of flu symptoms.
- Take it with food to avoid stomach upset.
- It is not a substitute for flu vaccination. You might be prescribed both by your doctor.
- Inform your doctor if you notice any changes in mood or behaviour, especially in children and adolescents.
Brief Description
Indication
Influenza
Administration
May be taken with or without food. May be taken w/ meals to reduce GI discomfort. Cap may be opened & mixed w/ sweetened food products eg chocolate syr, sweetened condensed milk, apple sauce or yogurt. Swallow mixture immediately after preparation.
Adult Dose
Oral
Treatment of Influenza A and B
Adult: 75 mg bid for 5 days. Initiate w/in 2 days of onset of symptoms.
Prophylaxis of influenza A and B
Adult: 75 mg once daily for at least 10 days. Initiate w/in 2 days of exposure. For community outbreak: May continue dosing for up to 6 wk.
Child Dose
Influenza A and B Treatment
1 year
40 kg: 75 mg PO q12hr x5 days
Dosing considerations
Start within 24-48 hours of symptom onset
Influenza A and B Prophylaxis
40 kg: 75 mg PO qDay x10 days
Dosing considerations
Start within 2 days of exposure
Renal Dose
Renal impairment: Haemodialysis patient: 30 mg after each dialysis session. Peritoneal dialysis patient: 30 mg as a single dose.
CrCl (ml/min) Dosage Recommendation
10-30 30 mg once daily.
>30-60 30 mg bid.
Contraindication
Hypersensitivity. Severe renal impairment.
Mode of Action
Oseltamivir is a prodrug of oseltamivir carboxylate (OC). OC is a potent selective competitive inhibitor of neuraminidase (an enzyme required for viral replication) of the influenza virus A and B. It prevents the release of viruses from infected host cell.
Precaution
Patient w/ resp disease, chronic cardiac disease. Renal and severe hepatic impairment. Immunocompromised patient. Childn. Pregnancy and lactation. Monitoring Parameters Monitor closely for signs and symptoms of behavioural changes.
Lactation: Unknown; use caution
Side Effect
1-10%
Abdominal pain,Conjunctivitis,Ear disorder,Epistaxis,Insomnia,Nausea,Vomiting,Vertigo
<1%
Aggravation of diabetes,Anemia,Arrhythmia,Confusion,Delirium,Hemorrhagic colitis,Hepatitis,Humerus fracture,Peritonsillar abscess,Pneumonia,Pseudomembranous colitis,Pyrexia,Rash,Seizure,Transaminases increased,Toxic epidermal necrolysis,Unstable angina,Swelling of face or tongue
Potentially Fatal: Anaphylaxis, severe dermatologic reactions.
Interaction
May potentially inhibit replication of influenza virus in live/attenuated influenza virus vaccine.
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