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Osiden
Square Pharmaceuticals PLC.
Generic: Adenosine
Safety Advices
বাংলা
English
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Osiden. Please consult your doctor.
CONSULT YOUR DOCTOR
Osiden may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
SAFE IF PRESCRIBED
Osiden is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
NOT RELEVANT
Not relevant, as Osiden is intended for use in hospitalised patients.
SAFE IF PRESCRIBED
Osiden is safe to use in patients with kidney disease. No dose adjustment of Osiden is recommended.
SAFE IF PRESCRIBED
Osiden is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Osiden may not be needed in these patients. Please consult your doctor.
Medicine Overview of Osiden 6mg/2ml Injection
Introduction
Osiden is an anti-arrhythmic medicine used to treat life-threatening arrhythmia (abnormal heart rhythm). It restores normal heart rhythm by blocking abnormal electrical signals in the heart. Osiden is also used to carry out diagnostic stress tests of the heart. It is administered under the supervision of a doctor. Your doctor will decide the dose and duration of the medicine for you. Doctor may closely monitor your blood pressure, heart rate and ECG till you became stable. You should continue all your other medicines that are advised by the doctor for your long-term treatment even after this injection. Common side effects...
... Show moreUses of Osiden
- Arrhythmia
Side effects of Osiden
Common
- Flushing (sense of warmth in the face, ears, neck and trunk)
- Dizziness
- Lightheadedness
- Nausea
- Numbness
- Tingling
- Chest pain
How to use Osiden
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Osiden works
Osiden is an anti-arrhythmic medication. It regulates heart beat by blocking abnormal electrical signals in the heart.
What if you forget to take Osiden?
If you miss a dose of Osiden, please consult your doctor.
Quick Tips
- Food and drinks containing caffeine such as chocolate, coffee, and tea must be avoided for at least 12 hours before medicine use.
- Stop taking medication and inform your doctor immediately if you experience a slow heartbeat, severe chest pain, and very low blood pressure.
- Inform your doctor if you have a history of fits or problems with your heart.
- Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Brief Description
Indication
Intravenous Differential diagnosis of supraventricular tachycardias Adult: Initially, 3 mg by rapid IV inj into a central or large peripheral vein over 2 sec with cardiac monitoring; 6 mg may be given after 1-2 minutes if necessary, then 12 mg after a further 1-2 minutes. Avoid increments if high level AV block occurs at any particular dose. Paroxysmal supraventricular tachycardia Adult: Initially, 3 mg by rapid IV inj into a central or large peripheral vein over 2 sec with cardiac monitoring; 6 mg may be given after 1-2 minutes if necessary, then 12 mg after a further 1-2 minutes. Avoid...
... Show moreAdministration
Adenosine effects antagonised by methylxanthines like caffeine, theophylline, etc. Concomitant carbamazepine may increase the risk of heart block.
Potentially Fatal: Adenosine effects are potentiated by dipyridamole.
Adult Dose
Pregnancy; heart transplant patients; patients on dipyridamole (lower initial dose of adenosine 0.5-1 mg); atrial fibrillation or flutter with accessory pathway (conduction along anomalous pathway may increase).
Lactation: Potential for serious adverse reactions in nursing infants; decision to interrupt nursing after administration of adenosine or not should take into account importance of drug to mother.
Renal Dose
Adenosine acts rapidly to slow down conduction through the AV node via the A1 receptors. It also mediates peripheral and coronary vasodilatation by stimulating the A2 receptors. Extremely short plasma half-life (<10 sec) permits dosage titration during IV use every 1-2 min and causes no concern of cumulative effect through repeated dosing.
Contraindication
Intravenous
Differential diagnosis of supraventricular tachycardias
Child: Initially, 50-100 mcg/kg; if necessary, may increase dose by 50-100 mcg/kg increments at 1-2 minute intervals or until arrhythmia is controlled. Max dose: 300 mcg/kg.
Paroxysmal supraventricular tachycardia
Child: Initially, 50-100 mcg/kg; if necessary, may increase dose by 50-100 mcg/kg increments at 1-2 minute intervals or until arrhythmia is controlled. Max dose: 300 mcg/kg.
Myocardial imaging
Adult: 140 mcg/kg/minute by infusion for 6 minutes. Inject radionuclide 3 minute after infusion.
Mode of Action
IV Administration
Adenocard: given as a rapid injection (1-3 sec) by peripheral IV route directly into vein or into IV line close (proximal) to patient & is followed by rapid NS flush after each inj (20 mL for adults, 5 mL or more for peds)
Place pt in mild reverse Trendelenburg position before giving drug.
Precaution
Paroxysmal supraventricular tachycardia, Supraventricular tachycardia
Pregnancy Category Note
>10%
Flushing (18%),Dyspnea (12%)
1-10%
Chest pain (7%),HA (2%),Lightheadedness (2%),Dizziness (1%),Tingling in arms (1%),Numbness (1%),Nausea (3%)
<1%
Hypotension,Palpitations,Apprehension,Head pressure,Chest pain,Hyperventilation,Blurred vision,Burning sensation,Heaviness in arms, neck & back pain,Metallic taste,Tightness in throat,Pressure in groin,Sweating
Interaction
2nd or 3rd degree AV block and sick sinus syndrome (unless pacemaker fitted), asthma, hypersensitivity.
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