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Oxiflam
The Ibn Sina Pharmaceutical Ind. Ltd.
Generic: Tenoxicam
Safety Advices
বাংলা
English
UNSAFE
It is unsafe to consume alcohol with Oxiflam.
CONSULT YOUR DOCTOR
Oxiflam may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
CONSULT YOUR DOCTOR
Information regarding the use of Oxiflam during breastfeeding is not available. Please consult your doctor.
UNSAFE
Oxiflam may cause side effects which could affect your ability to drive.
As Oxiflam may make you tired, drowsy, dizzy, have problems with your eyesight and balance, depressed or have difficulty sleeping and this may impair your ability to drive.
CAUTION
Oxiflam should be used with caution in patients with kidney disease. Dose adjustment of Oxiflam may be needed. Please consult your doctor.
Use of Oxiflam is not recommended in patients with severe kidney disease.
CAUTION
Oxiflam should be used with caution in patients with liver disease. Dose adjustment of Oxiflam may be needed. Please consult your doctor.
Use of Oxiflam is not recommended in patients with severe liver disease.
Medicine Overview of Oxiflam 20mg Tablet
Introduction
Oxiflam is a pain relieving medicine. It is used for the treatment of moderate to severe pain in conditions like osteoporosis and rheumatoid arthritis. Oxiflam should be taken with food. The dose and duration will depend on what you are taking it for and how well it helps your symptoms. You should keep taking the medicine even if you feel better until the doctor says it is alright to stop using it. The most common side effects of this medicine include mild vomiting, stomach pain, nausea, headache, and dizziness. If any of these side effects persist or get worse, you...
... Show moreUses of Oxiflam
- Pain relief
- Rheumatoid arthritis
Side effects of Oxiflam
Common
- Vomiting
- Nausea
- Stomach pain
- Indigestion
- Diarrhea
How to use Oxiflam
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Oxiflam is to be taken with food.
How Oxiflam works
Oxiflam is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that are responsible for inflammation (pain and swelling).
What if you forget to take Oxiflam?
If you miss a dose of Oxiflam, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
- Inform your doctor if you have ever been diagnosed with kidney or liver problems.
- It should be taken with food or milk to avoid getting an upset stomach.
- It can cause serious complications like stomach bleeding and kidney problems if taken for a long time.
- Oxiflam can raise your risk of blood clots, heart attack, or a stroke.
- Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
Brief Description
Indication
Pain and inflammation associated w/ musculoskeletal and joint disorders
Administration
Should be taken with food. Take w/ or immediately after meals.
Adult Dose
Oral
Acute musculoskeletal disorders; Osteoarthritis; Rheumatoid arthritis
Adult: 20 mg as a single dose, taken at the same time each day. Max: 40 mg/day (short term use).
Treatment duration: Up to 7 days for acute musculoskeletal disorders and up to 14 days for severe cases.
Elderly: Use the lowest effective dose for the shortest possible duration.
Contraindication
Active or history of recurrent GI bleed or peptic ulcer, hypersensitivity to NSAIDs, severe heart failure, haemorrhagic diathesis, asthma, pregnancy (3rd trimester).
Mode of Action
Tenoxicam is a potent inhibitor of prostaglandin synthesis by blocking the enzyme cyclo-oxygenase. Additional actions contributing to its anti-inflammatory effect includes inhibition of leucocyte function including phagocytosis and chemotaxis, and scavenging free O2 radicals. It has no effect on renal function at the usual doses.
Precaution
Patient w/ history of or active bronchial asthma, uncontrolled HTN, CHF, established ischaemic heart disease, peripheral arterial disease, cerebrovascular disease, risk factors for CV disease (e.g. HTN, hyperlipidaemia, DM, smoking), history of GI disease, fluid retention and oedema. Patient who will undergo major surgery (e.g. joint replacement). Elderly. Renal and hepatic impairment. Monitoring Parameters Monitor renal, hepatic and cardiac functions.
Side Effect
Dyspepsia, nausea, abdominal pain and discomfort, constipation, diarrhoea, flatulence, indigestion, epigastric distress, stomatitits, anorexia; peripheral oedema; headache, dizziness; allergic reactions, asthma, bronchospasm, dyspnoea, rash, pruritus; decreased Hb, anaemia, thrombocytopenia, non-thrombocytopenic purpura, leucopenia, eosinophilia, epistaxis; increased serum transaminase levels; swollen eyes, blurred vision, eye irritation, malaise, tinnitus; oedema, HTN, cardiac failure.
Potentially Fatal: Peptic ulceration, GI bleeding, anaphylaxis, Lyell's syndrome, Stevens-Johnson syndrome, exfoliative dermatitis, nephrotoxicity, arterial thrombotic events (e.g. MI or stroke), hepatitis, jaundice.
Interaction
Increased risk of adverse effects (particularly GI) w/ salicylates and other NSAIDs. May enhance the anticoagulant effect of warfarin and other anticoagulants. May reduce the effect of antihypertensive drugs. Increased risk of nephrotoxicity w/ ciclosporin. Increased risk of convulsions w/ quinolones. May decrease the elimination of lithium. May interfere w/ the natriuretic action of diuretics. May enhance the toxicity of methotrexate. May reduce the effects of mifepristone. Increased risk of GI bleeding w/ corticosteroids.
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