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Panalon

Name: Panalon Pancuronium Bromide Injection 4mg/2ml
Brand: Techno Drugs LTD.
SKU: 14419
Price: 249.98 BDT
Availability: OutOfStock
Rating: 4.8 (1 reviews)

Injection-(4mg/2ml)

Techno Drugs LTD.

Generic: Pancuronium Bromide

1 x 5 Injections

৳ 249.98

৳ 275

9% OFF

Medicine Overview of Panalon 4mg/2ml Injection

বাংলা

Introduction

Panalon belongs to a group of medicines called muscle relaxants. It is used along with general anesthesia or sedatives to provide skeletal muscle relaxation during surgical procedures. It is also used to facilitate emergency airway management in patients in intensive care. Panalon is generally administered by a healthcare professional. You should not self-administer this medicine at home. The dose and duration will depend on what you are taking it for and how well it helps your symptoms. The medicine is generally well-tolerated with little or no side effects. However, it may cause injection site reactions (such as pain, redness, and swelling), rash, and allergic reactions in some people. If any of these side effects persist or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms. Before using it, you should let your doctor know if you have any medical conditions or disorders. You should also tell your doctor all the other medicines you are using or taking. Pregnant and breastfeeding women should consult their doctors before using this medicine.

Uses of Panalon

Skeletal mucle relaxation during surgery

Side effects of Panalon

Common

Injection site reactions (pain, swelling, redness)

How to use Panalon

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Panalon works

Panalon relaxes the muscles by blocking the impulses from the nerves.

Brief Description

Indication

Adjunct to GA for Endotracheal intubation and to provide skeletal muscle ralaxation.

Adult Dose

General Anesthesia Adjunct/Cesarean Section Load: 0.04-0.1 mg/kg IV Maintenance: 0.015-0.1 mg/kg IV q30-60min OR Continuous infusion: 0.1 mg/kg/hr IV Dose should be calculated based on ideal body weight Monitoring of muscle twitch response to a peripheral nerve stimulator is advised Endotracheal Intubation Bolus dose 0.06-0.1 mg/kg Usually effective with in 2-3 minutes

Child Dose

Neonates (<28 Days Old) Load: 0.02 mg/kg IV Maintenance: 0.05-0.1 mg/kg IV q0.5-4hr PRN >1 Month Old Load: 0.04-0.1 mg/kg IV Maintenance: 0.015-0.1 mg/kg IV q30-60min OR Continual infusion: 0.1 mg/kg/hr IV

Contraindication

Anuria. Relatively contraindicated in conditions of reduced airway control. Lactation.

Mode of Action

Pancuronium bromide is a non-depolarising neuromuscular blocking agent with curarimimetic action through competitive blockade at the myoneural junction by binding with cholinergic receptor sites.

Precaution

Myasthenia gravis; severe electrolyte disorders; severe CV disease; pregnancy. Hepatic and renal function impairment. Hypothermia; jaundice; hypermagnesaemia, hypocalcaemia, hypokalaemia, hypoproteinaemia, acidosis, alkalosis, hypercalcemia. In obese patients, dose should be based on ideal body wt. Elderly; previous anaphylactic reactions to other neuromuscular-blocking agents. Burn patients (>30% of body) may be resistant to action for 5-70 days after injury. Demyelinating lesions, peripheral neuropathies, denervation, infection, muscle trauma, and DM may antagonise the neuromuscular blockade effects of drug. Neuromuscular diseases, acute intermittent porphyria, Eaton-Lambert syndrome. Maintain adequate airway and respiratory support during use. Lactation: not known if excreted in breast milk; effect on nursing infant not known

Side Effect

Tachycardia may occur due to vagal blockade and especially during light anaesthesia. May decrease intra-ocular pressure and induce miosis; excessive salivation; transient rashes and itching; wheezing; elevation in pulse rate, BP, cardiac output; erythema; burning sensation along vein; profound muscle weakness; bronchospasm; hypersensitivity reaction; acute quadriplegic myopathy syndrome, myositis ossificans. Potentially Fatal: Rare anaphylactoid reactions; bradycardia, bronchospasm, hypotension and CV collapse; respiratory depression.

Interaction

Neuroleptanalgaesia may decrease neuromuscular activity. Action may be prolonged and/or potentiated by aminoglycoside antibiotics, lithium, diazepam, lidocaine (high dose), quinidine, tetracyclines, propranolol, thiamine (high dose), parenteral magnesium sulphate, MAOIs, quinine, protamine, carbamazepine, donepezil and phenytoin (if pancuronium is given concurrently for <1 wk). Action may be decreased by neostigmine, edrophonium, high-dose or long term corticosteroids, adrenaline (may also potentiate effect), azathioprine, theophylline (high doses), clindamycin, nifedipine, piperacillin, polymixins, verapamil, procainamide. Furosemide may increase or decrease effects. TCAs may increase risk of arrhythmias and hypotension during anaesthesia. Potentially Fatal: Potentiated by volatile anaesthetics (isoflurane and enflurane) and local anaesthetics. Prior admin of suxamethonium can increase the intensity of neuromuscular block. Concomitant use with digoxin may increase risk of serious cardiac arrhythmias.

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Yes, Arogga delivers nationwide. You can order from anywhere in Bangladesh.

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Yes, Cash on Delivery is available across Bangladesh for most products.

How long does delivery take?

Delivery usually takes 24–48 hours inside Dhaka and 3–5 days outside Dhaka, depending on location and courier load.

Can I return or replace the product?

If the product is damaged, incorrect, or expired, you can request a replacement or refund according to Arogga’s return policy.

Safety Advices

CAUTION

Caution is advised when consuming alcohol with Panalon. Please consult your doctor.

CONSULT YOUR DOCTOR

Panalon may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.