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Safety Advices
বাংলা
English
UNSAFE
It is unsafe to consume alcohol with Pantrol.
CONSULT YOUR DOCTOR
Pantrol may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
CONSULT YOUR DOCTOR
Information regarding the use of Pantrol during breastfeeding is not available. Please consult your doctor.
CONSULT YOUR DOCTOR
It is not known whether Pantrol alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
CONSULT YOUR DOCTOR
There is limited information available on the use of Pantrol in patients with kidney disease. Please consult your doctor.
Use of Pantrol is not recommended in patients with severe kidney disease.
CAUTION
Pantrol should be used with caution in patients with liver disease. Dose adjustment of Pantrol may be needed. Please consult your doctor.
Use of Pantrol is not recommended in patients with moderate to severe liver disease.
Medicine Overview of Pantrol 12.5mg Tablet
Introduction
Pantrol is a pain relieving medicine. It helps relieve pain and reduces swelling, pain and redness in various joint conditions such as osteoarthritis and rheumatoid arthritis. It is also used for the treatment of migraine and menstrual pain. Pantrol can be taken with or without food. The dose depends on what you are taking it for and how well it helps your symptoms. You should take it as advised by your doctor and should not take more or use it for longer than recommended. The most common side effects of this medicine include flu-like symptoms, indigestion, edema, dizziness, headache, irregular...
... Show moreUses of Pantrol
- Pain relief
Side effects of Pantrol
Common
- Flu-like symptoms
- Peripheral edema
How to use Pantrol
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pantrol may be taken with or without food, but it is better to take it at a fixed time.
How Pantrol works
Pantrol is a non-steroidal anti-inflammatory drug (NSAID) called COX-2 inhibitors. It works by blocking the release of certain chemical messengers that are responsible for pain and inflammation (redness and swelling).
Quick Tips
- Pantrol helps relieve pain and inflammation.
- It may cause fewer stomach problems as compared to other NSAIDs like Ibuprofen or Naproxen.
- It may cause dizziness and fatigue. Do not drive or do anything requiring concentration until you know how it affects you.
- Do not consume alcohol while on treatment with this medicine as it may cause excessive drowsiness.
- Regularly monitor your blood pressure while taking this medicine, particularly in the first two weeks after starting treatment.
- Inform your doctor if you have a history of stomach ulcers, heart diseases, high blood pressure, and liver or kidney disease.
- During long-term treatment, your doctor may want to take regular blood tests to monitor your liver function.
- Do not take Pantrol if you are pregnant, planning to conceive, or breastfeeding.
Brief Description
Indication
Osteoarthritis, Rheumatoid arthritis, Pain
Adult Dose
Oral
Osteoarthritis
Adult: Initially, 12.5 mg once daily. Max: 25 mg/day.
Pain relief
Adult: Initially, 50 mg once daily followed by daily doses of 25-50 mg. Max: 50 mg/day. Treatment duration >5days is not recommended.
Rheumatoid arthritis
Adult: 25 mg daily. Max: 25 mg/day.
Hepatic Impairment Max: 12.5 mg/day.
Contraindication
Hypersensitivity. Severe renal impairment.
Mode of Action
Rofecoxib is a nonsteroidal anti-inflammatory drug (NSAID) that exhibits anti-inflammatory, analgesic, and antipyretic activities in animal models. The mechanism of action of (rofecoxib) is believed to be due to inhibition of prostaglandin synthesis, via inhibition of cyclooxygenase-2 (COX-2).
Precaution
Hepatic dysfunction, pregnancy and lactation. History of ulcer disease or GI bleeding. Elderly or debilitated patients. Prolonged treatment, smoking and alcoholism may increase risk of GI bleeding. Ischaemic heart disease.
Side Effect
Mouth ulcers, chest pain, weight gain, atopic eczema, muscle cramps, diarrhoea, headache, nausea; upper respiratory tract infection, hypertension, ischaemia, dyspepsia, epigastric discomfort, heart burn, nausea, sinusitis, back pain, headache, bronchitis, urinary tract infections.
Potentially Fatal: Renal failure; nephrotoxicity; MI.
Pregnancy Category Note
Pregnancy Category C, D (in 3rd trimester or near delivery)
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