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Parixol 180

Tablet-(180mcg)
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ACI Limited

Generic: Pramipexol

10 Tablets (1 Strip)
৳ 54.36
৳ 60.40
10% OFF

Medicine Overview of Parixol 180 180mcg Tablet

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Introduction

Parixol 180 is a prescription medicine used in the treatment of Parkinson's disease and restless leg syndrome (an urge to move the legs usually accompanied or caused by uncomfortable and unpleasant leg sensations). It helps to treat excessive shaking by slowing down the body movements. Parixol 180 should be taken with food. However, take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember it. You should never skip any doses and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to your doctor. Some common side effects of this medicine include nausea, dry mouth, fatigue, hallucinations, constipation, and peripheral edema. It also causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Inform your doctor if you develop any unusual changes in mood, an abnormally high sex drive, an urge to gamble or uncontrolled spending as these may prove very harmful.

Uses of Parixol 180

  • Parkinson's disease
  • Restless leg syndrome

Side effects of Parixol 180

Common
  • Dizziness
  • Sleepiness
  • Nausea
  • Dryness in mouth
  • Fatigue
  • Hallucination
  • Constipation
  • Peripheral edema

How to use Parixol 180

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Parixol 180 is to be taken with food.

How Parixol 180 works

Parixol 180 works by increasing the action of dopamine, a chemical messenger that is needed to control movement in the brain.

Quick Tips

  • You have been prescribed Parixol 180 to treat your symptoms of Parkinson's disease and/or restless leg syndrome.
  • It can be taken with or without food. Taking it with food may reduce nausea.
  • For restless leg syndrome, take this medicine 2 to 3 hours before bedtime.
  • Avoid activities that require you to be alert, such as driving a car until you know how this medication affects you.
  • When you first start taking Parixol 180, it may cause sudden drop in your blood pressure when you change positions. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
  • Talk to your doctor in case you develop hallucinations or other changes in your behavior.
  • Inform your doctor if you develop compulsive behaviors that are hard to control, such as binge eating, gambling, spending money, and sexual urges.
  • Do not stop taking the medication suddenly without talking to your doctor.

Brief Description

Indication

Parkinson's disease, Restless leg syndrome

Administration

May be taken with or without food. May be taken w/ meals to minimise GI side effects such as nausea.

Adult Dose

Parkinson Disease Immediate-release: 0.125 mg PO q8hr initially; gradually titrated upward at weekly intervals to target range of 1.5-4.5 mg/day PO divided q8hr Restless Legs Syndrome 0.125 mg/day PO 2-3 hr before bedtime initially; may be increased every 4-7 days up to 0.5 mg/day (every 14 days if CrCl 20-60 mL/min)

Renal Dose

Parkinson disease Immediate release CrCl >50 mL/min: Dosage adjustment not necessary CrCl 30-50 mL/min: 0.125 mg twice daily initially; not to exceed 0.75 mg TID CrCl 15-29 mL/min: 0.125 mg qDay; not to exceed 1.5 mg qDay CrCl <15 mL/min: Dosage adjustment not provided in manufacturer's labeling; not studied ESRD requiring hemodialysis: Dosage adjustment not provided in manufacturer's labeling; not studied Restless legs syndrome Immediate release CrCl >60 mL/min: Dosasge adjustment not necessary CrCl 20-60 mL/min: Dosage adjustment not necessary but duration between titration should be increased to 14 days CrCl<20 mL/min: Dosage adjustment not provided by manufacturer's labeling; not studied

Contraindication

Hypersensitivity. Lactation.

Mode of Action

Pramipexole is a nonergot-derivative dopamine receptor agonist which alleviates Parkinsonian motor deficits by directly stimulating postsynaptic dopamine activity on the striatum and substantia nigra It is used as an adjunct to levodopa for the symptomatic management of parkinsonian syndrome in patients w/ advanced disease. It is also used as monotherapy for the initial symptomatic management of parkinsonian syndrome.

Precaution

Psychotic disorder, severe CV disease, augmentation (earlier onset, increase and spread of symptoms). Risk of neuroleptic malignant syndrome w/ abrupt withdrawal. Taper dose at 750 mcg/day for a wk, then reduce by 375 mcg/day thereafter. Renal impairment. Pregnancy and lactation. Patient Counselling Patients should be informed to refrain from activities involving mental alertness and physical coordination after drug intake. Monitoring Parameters Monitor BP, signs and symptoms of fibrosis and orthostatic hypotension, development of impulse control disorder, behavioural changes. Perform periodic skin examinations. Regular ophthalmological testing due to risk of visual disorders.

Side Effect

>10% Somnolence,Dyskinesia,Hallucinations,Insomnia,Dizziness,Postural hypotension,Nausea,Constipation 1-10% (partial list) Abnormal dreams, thoughts, or vision,Amnesia,Confusion,Paranoia or delusion,Akathisia,Asthenia,Dry mouth

Interaction

Inhibits active tubular secretion of basic cationic drugs eg, cimetidine. Reduced clearance w/ drugs eliminated by active renal tubular secretion eg, amantadine. Alcohol & other sedatives.

Buy Parixol 180 from Arogga

In Bangladesh, you can get the original Parixol 180. Select your favorite one from a large collection of medicine products. Order from App to get more offers and better experience.

What is the price of Parixol 180 in Bangladesh?

The latest price of Parixol 180 in Bangladesh is 54.36৳. You can buy Parixol 180 at the best price from Arogga. Order online through our website or mobile app and get fast home delivery anywhere in Bangladesh. Cash on Delivery (COD) is available all over Bangladesh.

Frequently Questions & Answers

Is the product authentic?

Yes. Arogga sources all medicines and health products directly from trusted suppliers, distributors, or manufacturers. Every product is verified before delivery.

Does Arogga deliver all over Bangladesh?

Yes, Arogga delivers nationwide. You can order from anywhere in Bangladesh.

Is Cash on Delivery(COD) available?

Yes, Cash on Delivery is available across Bangladesh for most products.

How long does delivery take?

Delivery usually takes 24–48 hours inside Dhaka and 3–5 days outside Dhaka, depending on location and courier load.

Can I return or replace the product?

If the product is damaged, incorrect, or expired, you can request a replacement or refund according to Arogga’s return policy.

Safety Advices

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UNSAFE
Parixol 180 may cause excessive drowsiness with alcohol.
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CONSULT YOUR DOCTOR
Parixol 180 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
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CONSULT YOUR DOCTOR
Parixol 180 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. Parixol 180 suppresses serum prolactin and may interfere with breastfeeding.
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UNSAFE
Parixol 180 may cause side effects which could affect your ability to drive. Parixol 180 can cause hallucinations (seeing, hearing or feeling things that are not there). This may affect your ability to drive.
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CAUTION
Parixol 180 should be used with caution in patients with kidney disease. Dose adjustment of Parixol 180 may be needed. Please consult your doctor.
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SAFE IF PRESCRIBED
Parixol 180 is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Parixol 180 may not be needed in these patients. Please consult your doctor.

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Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.

Parixol 180 price in Bangladesh | Arogga Online Pharmacy