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Safety Advices
বাংলা
English
CAUTION
Caution is advised when consuming alcohol with Pavigard. Please consult your doctor.
UNSAFE
Pavigard is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
UNSAFE
Pavigard is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
SAFE
Pavigard does not usually affect your ability to drive.
CAUTION
Pavigard should be used with caution in patients with kidney disease. Dose adjustment of Pavigard may be needed. Please consult your doctor.
CAUTION
Pavigard should be used with caution in patients with liver disease. Dose adjustment of Pavigard may be needed. Please consult your doctor.
Use of Pavigard is not recommended in patients with active liver disease and severe liver disease.
Medicine Overview of Pavigard 2mg Tablet
Introduction
Pavigard belongs to a group of medicines called statins. It is used to lower cholesterol and to reduce the risk of heart disease. Cholesterol is a fatty substance that builds up in your blood vessels and causes narrowing, which may lead to a heart attack or stroke. Pavigard is a widely prescribed medicine and is regarded as safe for long-term use. It can be taken with a meal or on an empty stomach. You can take it at any time of the day but try to take it at the same time each day. Most people with high cholesterol do...
... Show moreUses of Pavigard
- High cholesterol
Side effects of Pavigard
Common
- Constipation
- Muscle pain
How to use Pavigard
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pavigard may be taken with or without food, but it is better to take it at a fixed time.
How Pavigard works
Pavigard is a lipid-lowering medication (statin). It works by blocking an enzyme (HMG-CoA-reductase) that is required in the body to make cholesterol. It thus lowers "bad" cholesterol (LDL) and triglycerides, raising the level of "good" cholesterol (HDL).
What if you forget to take Pavigard?
If you miss a dose of Pavigard, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
- It can be taken with or without food at any time of the day.
- It should be taken in addition to regular exercise and a low-fat diet to lower the levels of fat in the blood.
- Inform your doctor if you experience fatigue, muscle weakness or muscle pain.
- Your doctor may check your liver function before starting the treatment and regularly thereafter. Inform your doctor if you notice signs of liver problems such as stomach pains, unusually dark urine or yellowing of skin or eyes.
- Inform your doctor if you have kidney disease, liver disease or diabetes before starting treatment with this medicine. If you are diabetic, monitor your blood sugar level regularly as Pavigard may cause an increase in your blood sugar level.
- Do not take Pavigard if you are pregnant, planning a pregnancy or breastfeeding.
Brief Description
Indication
Hypercholesterolaemia, Hyperlipidaemias, Mixed dyslipidaemia, Cardiovascular disease,
Administration
May be taken with or without food.
Adult Dose
Oral
Hypercholesterolemia
Adult: 2 mg once daily.
May increase to 4 mg qDay if necessary.
Hepatic Impairment
Contraindicated in active liver disease or unexplained transaminase elevations
Child Dose
Safety and efficacy not established
Renal Dose
Renal impairment: Moderate to severe (CrCl 15-60 mL/min, not on haemodialysis) and ESRD (on haemodialysis): Initial: 1 mg once daily. Max: 2 mg once daily.
Contraindication
Patients with a known hypersensitivity to any component of this products. Pitavastatin is contraindicated in patients with active liver disease , which may include unexplained persistent elevations of hepatic transaminase levels.
Mode of Action
HMG-CoA reductase inhibitor, inhibits rate-limiting step in cholesterol biosynthesis by competitively inhibiting HMG-CoA reductase
Precaution
Patient w/ predisposing factors for myopathy; alcoholism. Renal impairment. Monitoring Parameters Monitor lipid panel (total cholesterol, HDL, LDL, triglycerides), hepatic transaminase levels; creatine phosphokinase (CPK).
Lactation: Contraindicated
Side Effect
Liver enzyme abnormalities, myalgia, muscle spasm, back pain, diarrhoea, constipation, pain in extremities, arthralgia, headache, dizziness, influenza, nasopharyngitis, abdominal discomfort, abdominal pain, dyspepsia, nausea, asthenia, malaise, fatigue, hepatitis, jaundice, hypoaesthesia, insomnia, depression, interstitial lung disease, erectile dysfunction, cognitive impairment (e.g. memory loss and impairment, confusion, forgetfulness, amnesia).
Potentially Fatal: Myopathy and rhabdomyolysis w/ acute renal failure secondary to myoglobinuria; hepatic failure.
Interaction
Increased bioavailability w/ erythromycin and rifampicin. Increased risk of myopathy/rhabdomyolysis w/ gemfibrozil, colchicine, niacin and other fibrates.
Potentially Fatal: Ciclosporin significantly increases pitavastatin exposure.
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