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Pegfilgrast

Injection-(6mg/0.6ml)
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Beacon Pharmaceuticals PLC

Generic: Pegfilgrastim

1 Injection
৳ 14400
৳ 18000
20% OFF
Alternative Brands For Pegfilgrast

Medicine Overview of Pegfilgrast 6mg/0.6ml Injection

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Introduction

Pegfilgrast is used to prevent infections after chemotherapy. It is a growth factor that stimulates bone marrow to produce white blood cells. These cells protect the body against infections. Pegfilgrast is given as an injection by a qualified medical professional. You should continue to take as long as your doctor advises for it. The duration of treatment varies according to your need and response to treatment. You might be asked for regular tests done to check the number of blood cells in your blood and your bone density level while you are taking this medicine. The most common side effects of this medicine include bone pain, joint pain, headache, nausea, and muscle pain. Other than this, pain or redness at the site of injection is common. But, inform your doctor if you notice a lump, swelling, or bruising that does not go away. It might not prevent you from all kinds of infection, hence inform your doctor if you notice fever, chills, shortness of breath, sore throat and swelling around face or neck. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You must avoid driving or attention-seeking activity if you experience dizziness after taking this medicine.

Uses of Pegfilgrast

  • Infections after chemotherapy

Side effects of Pegfilgrast

Common
  • Bone pain
  • Joint pain
  • Headache
  • Nausea
  • Low blood platelets
  • Muscle pain
  • Back pain
  • Pain in extremity
  • Injection site pain

How to use Pegfilgrast

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Pegfilgrast works

Pegfilgrast is a growth factor that stimulates the bone marrow to produce white blood cells. These cells protect the body against infections. .

What if you forget to take Pegfilgrast?

If you miss a dose of Pegfilgrast, please consult your doctor.

Quick Tips

  • Pegfilgrast reduces the risk of infection in people treated with chemotherapy.
  • It is usually given as a daily injection into the tissue just under the skin or into the vein.
  • You will normally receive your first dose at least 24 hours after your chemotherapy or bone marrow transplant.
  • Store it in the refrigerator, protect it from light, and don't shake it.
  • For a more comfortable injection, leave the syringe at room temperature for 30 minutes before using it.
  • Pain or redness in the area of injection is common. Let your doctor know if you notice a lump, swelling, or bruising that doesn't go away.
  • Use caution while driving or doing anything that requires concentration as Pegfilgrast may cause dizziness.
  • Your doctor may get regular tests done to monitor the number of blood cells in your blood, and your bone density level while you are receiving treatment with this medicine.
  • Stop taking Pegfilgrast and inform your doctor if you have a fever, shortness of breath, fast rate of breathing or trouble breathing.

Brief Description

Indication

Chemotherapy induced-neutropenia, Bone marrow stimulation

Adult Dose

Subcutaneous Chemotherapy-induced neutropenia, Myelosuppressive Chemotherapy Adjunct Indicated to decrease incidence of infection in patients with non-myeloid malignancies receiving myelosuppressive chemotherapy assoc with febrile neutropenia Adult: 6 mg as a single dose for each chemotherapy cycle, given at least 24 hr after cytotoxic chemotherapy.

Child Dose

Subcutaneous Prevention of Chemotherapy Induced Neutropenia <45 kg: 100 mcg/kg per chemotherapy cycle; not to exceed 6 mg/dose; do not administer in the period 14 days before and 24-72 hr after administration of cytotoxic chemotherapy >45kg: 6 mg SC once per chemotherapy cycle; do not administer in the period 14 days before and 24 hr after administration of cytotoxic chemotherapy

Contraindication

Hypersensitivity to Pegfilgrastim or filgrastim; or to any ingredients in the formulation.

Mode of Action

Pegfilgrastim is a covalent conjugate of filgrastim and monomethoxypolyethyleneglycol (PEG). It is a colony-stimulating factor which binds to specific cell surface receptors of haematopoietic cells, thereby stimulating proliferation, differentiation, commitment, and end cell functional activation. Pegfilgrastim has delayed renal clearance and prolonged half-life relative to filgrastim as a result of conjugation with PEG.

Precaution

Splenic rupture (including fatal cases) or enlarged spleen have been reported following admin of Pegfilgrastim; patients who reported left upper abdominal or shoulder tip pain should be evaluated for development of splenomegaly or splenic rupture. Acute respiratory distress syndrome (ARDS) may occur; monitor patients for pulmonary symptoms e.g. cough, fever, lung infiltrates, or respiratory distress. Discontinue or withhold Pegfilgrastim in patients with confirmed ARDS. Caution in patients with existing sickle cell disorders; as severe sickle cell crisis may occur. Possibility of Pegfilgrastim acting as a growth factor for any tumor type cannot be excluded. Not approved for myeloid malignancies and myelodysplasia. Monitor platelet count and haematocrit regularly. Do not administer Pegfilgrastim during the 14 days before and 24 hr after chemotherapy admin due to the potential sensitivity of rapidly dividing myeloid cells to cytotoxic chemotherapy. Safety and efficacy in paediatric patients have not been established. Pregnancy and lactation.

Side Effect

>10% Peripheral edema (12%),Asthenia (13%),Headache (16%),Vomiting (13%),Bone pain (31-57%),Myalgia (21%),Weakness (13%),Alopecia (15-72%),Pyrexia (23%) Frequency Not Defined Acute respiratory distress syndrome,Sickle cell crisis,Splenic rupture,Hyperuricemia,Elevated lactate dehydrogenase,Elevated alkaline phosphatase,Allergic reaction Potentially Fatal: Anaphylaxis.

Interaction

Colony-stimulating factors such as Pegfilgrastim should not be given at the same time as cytotoxic chemotherapy due to the increased risk of myelosuppression.

Buy Pegfilgrast from Arogga

In Bangladesh, you can get the original Pegfilgrast. Select your favorite one from a large collection of medicine products. Order from App to get more offers and better experience.

What is the price of Pegfilgrast in Bangladesh?

The latest price of Pegfilgrast in Bangladesh is 14400৳. You can buy Pegfilgrast at the best price from Arogga. Order online through our website or mobile app and get fast home delivery anywhere in Bangladesh. Cash on Delivery (COD) is available all over Bangladesh.

Frequently Questions & Answers

Is the product authentic?

Yes. Arogga sources all medicines and health products directly from trusted suppliers, distributors, or manufacturers. Every product is verified before delivery.

Does Arogga deliver all over Bangladesh?

Yes, Arogga delivers nationwide. You can order from anywhere in Bangladesh.

Is Cash on Delivery(COD) available?

Yes, Cash on Delivery is available across Bangladesh for most products.

How long does delivery take?

Delivery usually takes 24–48 hours inside Dhaka and 3–5 days outside Dhaka, depending on location and courier load.

Can I return or replace the product?

If the product is damaged, incorrect, or expired, you can request a replacement or refund according to Arogga’s return policy.

Safety Advices

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CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Pegfilgrast. Please consult your doctor.
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CONSULT YOUR DOCTOR
Pegfilgrast may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
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SAFE IF PRESCRIBED
Pegfilgrast is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
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SAFE
Pegfilgrast does not usually affect your ability to drive.
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SAFE IF PRESCRIBED
Pegfilgrast is safe to use in patients with kidney disease. No dose adjustment of Pegfilgrast is recommended.
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CONSULT YOUR DOCTOR
There is limited information available on the use of Pegfilgrast in patients with liver disease. Please consult your doctor.

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Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.