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Proactin
Eskayef Pharmaceuticals Ltd.
Generic: Cyproheptadine HCI
Safety Advices
বাংলা
English
UNSAFE
Proactin may cause excessive drowsiness with alcohol.
SAFE IF PRESCRIBED
Proactin is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
SAFE IF PRESCRIBED
Proactin is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Unless Proactin is used to lower the prolactin levels in the mother, it should be avoided as it might interfere with breastfeeding.
UNSAFE
Proactin may cause side effects which could affect your ability to drive.
Proactin may cause dizziness, sedation, and hypotension in elderly patients. This may affect your ability to drive.
CAUTION
Proactin should be used with caution in patients with severe kidney disease. Dose adjustment of Proactin may be needed. Please consult your doctor.
CONSULT YOUR DOCTOR
There is limited information available on the use of Proactin in patients with liver disease. Please consult your doctor.
Medicine Overview of Proactin 4mg Tablet
Introduction
Proactin belongs to a group of medicines called antihistamines. It is used in the treatment of various allergic conditions. It relieves symptoms like itching, swelling and rashes. It is also used to treat loss of appetite (need for food). It is an effective hunger stimulant. Proactin can be taken with or without food and it is better to take it in a dose and duration as advised by the doctor. You may need this medicine only on days you have symptoms, or you may need to take it every day to prevent symptoms from happening. If you stop taking it...
... Show moreUses of Proactin
- Appetite stimulant
Side effects of Proactin
Common
- Increased appetite
How to use Proactin
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Proactin may be taken with or without food, but it is better to take it at a fixed time.
How Proactin works
Proactin is an antihistaminic medication. It blocks the action of certain chemical messengers that are responsible for inflammation, congestion, itching, and other allergic reactions.
What if you forget to take Proactin?
If you miss a dose of Proactin, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
- Avoid driving or operating dangerous machinery as it may decrease alertness.
- Avoid consuming alcohol when taking the Proactin, as it may cause excessive sleepiness or drowsiness.
Brief Description
Indication
Rash, pruritus in a variety of condition, appetite stimulation, anorexia nervosa, cushing's syndrome, Nelson's syndrome, acromegaly, hyperprolactinemia, migraine, antidepressant-induced inorgasmia
Administration
May be taken with or without food. May be taken w/ meals to reduce GI discomfort.
Adult Dose
Oral
Allergic conditions
Adult: Initially, 4 mg tid, adjusted as necessary. Usual: 12-16 mg daily in 3-4 divided doses. Max: 32 mg/day.
Treatment and prophylaxis of migraine and other vascular headaches
Adult: 4 mg may be repeated after 30 min. Not to exceed 8 mg w/in a 4- to 6-hr period. Maintenance: 4 mg 4-6 hrly.
Child Dose
Oral
Allergic conditions
Child: 2-6 yr 2 mg bid or tid. Max: 12 mg daily;
7-14 yr 4 mg bid or tid. Max: 16 mg daily.
Migraine
Prophylaxis
3 years and adolescents: 0.2-0.4 mg/kg/day PO divided BID; not to exceed 0.5 mg/kg/day
Contraindication
Narrow-angle glaucoma; acute asthmatic attack; bladder neck obstruction; stenosing peptic ulcer; GIT obstruction; MAOIs therapy; hypersensitivity; neonates, lactation.
Mode of Action
Cyproheptadine is a sedating antihistamine w/ antimuscarinic, serotonin antagonist and Ca channel blocking properties. It competes w/ histamine for H1-receptor sites on effector cells in the GI tract, blood vessels and resp tract.
Precaution
Elderly; epilepsy; tasks requiring mental alertness; symptomatic prostate hypertrophy; epilepsy; alcoholism; pregnancy.
Lactation: Excretion in milk unknown; contraindicated
Side Effect
Psychiatric/neurologic: CNS depression, drowsiness, sedation ranging from mild drowsiness to deep sleep (most frequent), dizziness, lassitude, disturbed coordination; less commonly, restlessness, insomnia, tremors, euphoria, nervousness, irritability, delirium, seizures, toxic psychosis, paresthesia Muscular: Weakness Cardiovascular: Palpitation, tachycardia, palpitation, ECG changes (eg, widened QRS), arrhythmias (eg, extrasystole, heart block), hypotension, hypertension, dizziness, sedation, hypotension GI: Epigastric distress, anorexia, nausea, vomiting, diarrhea, constipation Hepatic: Cholestasis, hepatitis, hepatic failure, hepatic function abnormality, jaundice (rare) Skin: Eczema, pruritus, inflammation, papular rash, erythema on exposed skin Sensory: Visual disturbances, blurred vision, diplopia, tinnitus, acute labyrinthitis Renal: Dysuria, urinary retention Respiratory: Thickening of bronchial secretions, wheezing, nasal...
... Show morePregnancy Category Note
Pregnancy category: B
Lactation: Excretion in milk unknown; contraindicated
Interaction
May have additive effects w/ CNS depressants e.g. hypnotics, sedatives, tranquilizers, antianxiety agents.
Potentially Fatal: MAOIs prolong and intensify the anticholinergic effects of antihistamines.
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