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Safety Advices
বাংলা
English
UNSAFE
Consuming alcohol while taking Pronil may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
CONSULT YOUR DOCTOR
Pronil may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
CAUTION
Pronil should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
UNSAFE
Pronil may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
CONSULT YOUR DOCTOR
There is limited information available on the use of Pronil in patients with kidney disease. Please consult your doctor.
SAFE IF PRESCRIBED
Pronil is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Pronil may not be needed in these patients. Please consult your doctor.
Medicine Overview of Pronil 500mg Tablet
Introduction
Pronil is an antibiotic medicine that helps your body fight infections caused by bacteria and parasites. It is used to treat infections of the liver, stomach, intestines, vagina, brain, heart, lungs, and skin. Pronil is also used in the treatment of dental infections, leg ulcers and pressure sores. This medicine may be taken with or without food. However, it should be taken at the same time each day to get the most benefit. The amount you are advised will depend on what you are being treated for and how bad it is, but you should take this antibiotic exactly as...
... Show moreUses of Pronil
- Bacterial & parasitic infections
Side effects of Pronil
Common
- Headache
- Nausea
- Vomiting
- Abdominal pain
- Diarrhea
- Vaginal itching
- Vaginal yeast infection
How to use Pronil
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pronil is to be taken with food.
How Pronil works
Pronil is an antibiotic. It kills the bacteria and other microorganisms that cause infections by damaging their DNA.
What if you forget to take Pronil?
If you miss a dose of Pronil, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
- Always take the complete course of treatment, as advised by your doctor, even if you feel better.
- It may cause side effects like nausea, stomach upset, and a metallic taste in the mouth.
- Pronil used in a high dose or for a prolonged time increases the risk of side effects such as nerve damage. Take it only as prescribed by your doctor.
- Do not drink alcohol during or for 2-3 days after treatment with this medicine. You may develop nausea, vomiting, flushing and headache.
- Inform your doctor if you have liver disease. Your dose may need to be adjusted in severe liver disease.
- Pronil treats infections caused by bacteria and parasites.
- It may also be used to prevent infections following surgery.
Brief Description
Indication
Giardiasis, Amoebiasis, Trichomoniasis
Adult Dose
Oral
Trichomoniasis; Amoebiasis; Giardiasis
Adult: 2 g as a single dose.
Severe invasive amoebiasis
Adult: 1.5 g daily as single or in divided doses for 5 days.
Child Dose
Oral
Trichomoniasis; Amoebiasis; Giardiasis
Child: 30 mg/kg as a single dose.
Severe invasive amoebiasis
Child: 30 mg/kg daily for 5 days.
Contraindication
Hypersensitivity; pregnancy (1st trimester) and lactation.
Mode of Action
Secnidazole is active against E histolytica, G lamblia, T vaginalis, Clostridium spp, B fragilis, Gardnerella spp. The drug enters the microorganisms by diffusion and is reduced intracellularly by low oxidation-reduction potential ferredoxin which then result in DNA damage.
Precaution
Avoid alcohol and disulfiram. Avoid in patients with history of blood disorders.
Side Effect
Nausea, gastralgia, change of taste, metallic taste, stomatitis, urticaria, rashes, leucopenia. Rarely vertigo, moderate neurological, digestive disturbances.
Interaction
Concurrent disulfiram admin may cause psychotic reactions. Disulfiram-like reactions with alcohol. Cimetidine may prolong half-life.
Potentially Fatal: May potentiate anticoagulant effect of warfarin and increase risk of haemorrhage.
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